Human AGT-p.Met268Thr and coronary heart disease risk: a case-control study and meta-analysis

• Authors: Hanieh Mohammadi , Narges Razavi , Abbasi Ali , Babaei Faezeh , Seyedrezazadeh Ensiyeh , Hosseinzade Abasalt
• Languages of publication: EN

Keywords

EN

coronary disease; angiotensinogen; genetic polymorphism; meta-analysis.

• Publisher: Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
• Journal: Family Medicine & Primary Care Review
• Year: 2018
• Issue: 1
• Pages: 17-24

Contributors

author

Hanieh Mohammadi

author

Narges Razavi

author

Abbasi Ali

author

Babaei Faezeh

author

Seyedrezazadeh Ensiyeh

author

Hosseinzade Abasalt

References

• Libby P, Theroux P. Pathophysiology of coronary artery disease. Circulation 2005; 111(25): 3481–3488.
• Wilson PW. Established risk factors and coronary artery disease: the Framingham Study. Am J Hypertens 1994; 7(7 Pt 2): 7S–12S.
• El-Aziz TAA, Hussein YM, Mohamed RH, et al. Renin–angiotensin system genes polymorphism in Egyptians with premature coronary artery disease. Gene 2012; 498(2): 270–275.
• Zdravkovic S, Wienke A, Pedersen N, et al. Heritability of death from coronary heart disease: a 36‐year follow‐up of 20 966 Swedish twins. J Intern Med 2002; 252(3): 247–254.
• Khera AV, Kathiresan S. Genetics of coronary artery disease: discovery, biology and clinical translation. Nat Rev Genet 2017; 18(6):331–344.
• Altshuler D, Daly MJ, Lander ES. Genetic mapping in human disease. Science 2008; 322(5903): 881–888.
• Zuk O, Schaffner SF, Samocha K, et al. Searching for missing heritability: designing rare variant association studies. Proc Natl Acad Sci USA 2014; 111(4): E455–E464.
• Nikpay, Goel A, Won HH. A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease.Nat Genet 2015; 47(10): 1121–1130.
• Do AN, Irvin MR, Lynch AI, et al. The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study. Front Pharmacol 2014; 5: 210, doi: 10.3389/fphar.2014.00210.
• Singh KD, Karthikeyan M. Combined sequence and sequence-structure-based methods for analyzing RAAS gene SNPs: a computational approach. J Recept Signal Transduct 2014; 34(6): 513–526.
• Pedrinelli R, Ballo P, Fiorentini C, et al. Hypertension and stable coronary artery disease: an overview. J Cardiovasc Med (Hagerstown)2013; 14(8): 545–552.
• Poorgholi L, Saffar H, Fathollahi MS, et al. Angiotensin – converting enzyme insertion/deletion polymorphism and its association with coronary artery disease in an Iranian population. J Tehran Heart Cent 2013; 8(2): 89–94.
• Ohishi M, Yamamoto K, Rakugi H. Angiotensin (1–7) and other angiotensin peptides. Curr Pharm Des 2013; 19(17): 3060–3064.
• Katsuya T, Morishita R. Gene polymorphism of angiotensin II type 1 and type 2 receptors. Curr Pharm Des 2013; 19(17): 2996–3001.
• Joshi PH, Xu H, LeStrange R, et al. The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease. Atherosclerosis 2013; 226(2): 433–439.
• Renner W, Nauck M, Winkelmann BR, et al. Association of angiotensinogen haplotypes with angiotensinogen levels but not with blood pressure or coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health Study. J Mol Med 2005; 83(3): 235–239.
• Tsai CT, Hwang JJ, Ritchie MD, et al. Renin–angiotensin system gene polymorphisms and coronary artery disease in a large angiographic cohort: detection of high order gene–gene interaction. Atherosclerosis 2007; 195(1): 172–180.
• Wenzel K, Blackburn A, Ernst M, et al. Relationship of polymorphisms in the renin–angiotensin system and in E-selectin of patients with early severe coronary heart disease. J Mol Med 1997; 75(1): 57–61.
• Żak I, Balcerzyk A, Sarecka B, et al. Contemporaneous carrier-state of two or three “proatherosclerotic” variants of APOE, ICAM1,PPARA and PAI-1 genes differentiate CAD patients from healthy individuals. Clin Chim Acta 2005; 362(1–2) 110–118.
• Nalbantoglu S, Tabel Y, Mir S, et al. Association between RAS gene polymorphisms (ACE I/D, AGT M235T) and Henoch-Schönlein purpura in a Turkish population. Dis Markers 2013; 34(1): 23–32.
• Hossienzadeh CA, Moradi FH, Karimian M. Optimal conditions for amplification of microsatellite length polymorphisms such as poly (A)in 3’ UTR of VDR gene. G3M 2016; 14(2): 4256–4261.
• Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22(4):719–748.
• DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7(3): 177–188.
• Sharif A, Kheirkhah D, Sharif MR, et al. ABCB1-C3435T polymorphism and breast cancer risk: a case-control study and a meta-analysis.J BUON 2016; 21(6): 1433–1441.
• Ermis C, Tsai MY, Hanson NQ, et al. Angiotensin I converting enzyme, angiotensin II type 1 receptor and angiotensinogen polymorphisms and early myocardial infarction in Turkish population. Thromb Haemost 2002; 88: 693–694.
• Frossard PM, Hill SH, Elshahat YI, et al. Associations of angiotensinogen gene mutations with hypertension and myocardial infarction in a gulf population. Clin Genet 1998; 54(4): 285–293.
• Gardemann A, Stricker J, Humme J, et al. Angiotensinogen T174M and M235T gene polymorphisms are associated with the extent of coronary atherosclerosis. Atherosclerosis 1999; 145(2): 309–314.
• 28. Hooper WC, Dowling NF, Wenger NK, et al. Relationship of venous thromboembolism and myocardial infarction with the renin–angiotensin system in African–Americans. Am J Hematol 2002; 70(1): 1–8.
• Ichihara S, Yokota M, Fujimura T, et al. Lack of association between variants of the angiotensinogen gene and the risk of coronary artery disease in middle-aged Japanese men. Am Heart J 1997; 134(2 Pt 1): 260–265.
• Jurkovicova D, Sedlakova B, Riecansky I, et al. Cardiovascular diseases and molecular variants of the renin–angiotensin system components in Slovak population. Gen Physiol Biophys 2007; 26: 27–32.
• Katsuya T, Koike G, Yee TW, et al. Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease.Lancet 1995; 345(8965): 1600–1603.
• Ko YL, Ko YS, Wang SM, et al. Angiotensinogen and angiotensin-I converting enzyme gene polymorphisms and the risk of coronary artery disease in Chinese. Hum Genet 1997; 100(2): 210–214.
• Konopka A, Szperl M, Piotrowski W, et al. Influence of renin–angiotensin system gene polymorphisms on the risk of ST-segment-elevation myocardial infarction and association with coronary artery disease risk factors. Mol Diagn Ther 2011; 15(3): 167–176.
• Ludwig E, Borecki I, Ellison R, et al. Associations between candidate loci angiotensin-converting enzyme and angiotensinogen with coronary heart disease and myocardial infarction: the NHLBI Family Heart Study. Ann Epidemiol 1997; 7(1): 3–12.
• Méthot J, Hamelin BA , Bogaty P, et al. ACE-DD genotype is associated with the occurrence of acute coronary syndrome in postmenopausal women. Int J Cardiol 2005; 105(3): 308–314.
• Motawi T, Shaker O, Taha M, et al. Endothelial nitric oxide synthase and angiotensinogen gene polymorphism in coronary artery diseases in Egypt. Angiology 2011; 62(2): 191–197.
• Nair K, Shalia K, Ashavaid T, et al. Coronary heart disease, hypertension, and angiotensinogen gene variants in Indian population. J Clin Lab Anal 2003; 17(5): 141–146.
• Niemiec P, Zak I, Wita K. The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia. Eur J Epidemiol 2008; 23(5): 349–354
• Olivieri O, Stranieri C, Girelli D, et al. Homozygosity for angiotensinogen 235T variant increases the risk of myocardial infarction in patients with multi-vessel coronary artery disease. J Hypertens 2001; 19(5): 879–884.
• Ortlepp JR, Lauscher J, Janssens U, et al. Analysis of several hundred genetic polymorphisms may improve assessment of the individual genetic burden for coronary artery disease. Eur J Intern Med 2002; 13(8): 485–492.
• Ranjith N, Pegoraro R, Rom L, et al. Renin–angiotensin system and associated gene polymorphisms in myocardial infarction in young South African Indians: cardiovascular topics. Cardiovasc J S Afr 2004; 15(1): 22–26.
• Rodrıǵ uez-Pérez JC, Rodrıǵ uez-Esparragón F, Hernández-Perera O, et al. Association of angiotensinogen M235T and A(-6)G gene polymorphisms with coronary heart disease with independence of essential hypertension: the PROCAGENE study. J Am Coll Cardiol 2001;37(6): 1536–1542.
• Sekuri C, Cam FS, Ercan E, et al. Renin–angiotensin system gene polymorphisms and premature coronary heart disease. J Renin Angiotensin Aldosterone Syst 2005; 6(1): 38–42.
• Sethi AA, Tybjaerg-Hansen A, Gronholdt M, et al. Angiotensinogen mutations and risk for ischemic heart disease, myocardial infarction,and ischemic cerebrovascular disease. Six case-control studies from the Copenhagen City Heart Study. Ann Intern Med 2001; 134(10):941–954.
• Sheu WH, Lee W, Jeng C, et al. Angiotensinogen gene polymorphism is associated with insulin resistance in nondiabetic men with or without coronary heart disease. Am Heart J 1998; 136(1): 125–131.
• Tiret L, Blanc H, Ruidavets JB, et al. Gene polymorphisms of the renin–angiotensin system in relation to hypertension and parental history of myocardial infarction and stroke: the PEGASE study. Projet d’Etude des Gènes de l’Hypertension Artérielle Sévère à modérée Essentielle. J Hypertens 1998; 16(1): 37–44.
• 47. Wierzbicki AS, Lambert-Hammill M, Lumb PJ, et al. Renin–angiotensin system polymorphisms and coronary events in familial hypercholesterolemia.Hypertension 2000; 36(5): 808–812.
• Winkelmann BR, Russ AP, Nauck M, et al. Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease. Am Heart J 1999; 137(4 Pt 1): 698–705.
• Yamakawa-Kobayashi K, Arinami T, Hamaguchi H. Absence of association of angiotensinogen gene T235 allele with increased risk of coronary heart disease in Japanese. Lancet 1995; 346(8973): 515.
• Zafarmand MH, Van Der Schouw YT, Grobbee DE, et al. The M235T polymorphism in the AGT gene and CHD risk: evidence of a Hardy–Weinberg equilibrium violation and publication bias in a meta-analysis. PLoS ONE 2008; 3(6): e2533, doi: 10.1371/journal.pone.0002533.
• Mazaheri M, Karimian M, Behjati M, et al. Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: a case-control study and a computational analysis. Ir J Med Sci 2017; 186(4): 921–928.
• Dzau VJ. Cell biology and genetics of angiotensin in cardiovascular disease. J Hypertens Suppl 1994; 12(4): S3–S10.
• Raynolds MV, Ferryman MB. The association between the angiotensin I converting enzyme gene polymorphism and cardiovascular disease. Coron Artery Dis 1995; 6(4): 302–309.
• Jamali S, Karimian M, Nikzad H, et al. The c.− 190 C> a transversion in promoter region of protamine1. Mol Biol Rep 2016; 43: 795–802.
• Soleimani Z, Kheirkhah D, Sharif MR, et al. Association of CCND1 Gene c. 870G> A polymorphism with breast cancer risk: a case-control study and a meta-analysis. Pathol Oncol Res 2017; 23(3): 621–631.
• Zamani-Badi T, Karimian M, Azami-Tameh A, et al. Association of C3953T transition in interleukin 1β gene with idiopathic male infertility in an Iranian population. Hum Fertil (Camb) 2017: 1–7, doi: 10.1080/14647273.2017.1384857.
• Karimian M, Hosseinzadeh Colagar A. Human MTHFR-G1793A transition may be a protective mutation against male infertility: a genetic association study and in silico analysis. Hum Fertil (Camb) 2017: 1–9, doi: 10.1080/14647273.2017.
• Salimi S, Keshavarzi F, Mohammadpour-Gharehbagh A, et al. Polymorphisms of the folate metabolizing enzymes: association with SLE susceptibility and in silico analysis. Gene 2017; 637: 161–172.
• Talebi E, Karimian M, Nikzad H. Association of sperm mitochondrial DNA deletions with male infertility in an Iranian population. Mitochondrial DNA A DNA Mapp Seq Anal 2017: 1–9, doi: 10.1080/24701394.2017.1331347.
• Karimian M, Nikzad H, Azami-Tameh A, et al. SPO11-C631T gene polymorphism: association with male infertility and an in silicoanalysis.J Family Reprod Health 2015; 9(4): 155–163.
• Ebrahimi A, Hosseinzadeh Colagar A, Karimian M. Association of human methionine synthase-A2756G transition with prostate cancer:a case-control study and in silico analysis. Acta Med Iran 2017; 55(5): 297–303.
• Raygan F, Karimian M, Rezaeian A, et al. Angiotensinogen-M235T as a risk factor for myocardial infarction in Asian populations: a genetic association study and a bioinformatics approach. Croat Med J 2016; 57(4): 351–362.
• Abchee A, El-Sibai M, Youhanna S, et al. The I allele of the angiotensin converting enzyme I/D polymorphism confers protection against coronary artery disease. Coron Artery Dis 2010; 21: 151–156.
• Xu MQ, Ye Z, Hu FB, et al. Quantitative assessment of the effect of angiotensinogen gene polymorphisms on the risk of coronary heart disease. Circulation 2007; 116(2): 1356–1366.
• Li X, Li Q, Wang Y, et al. AGT gene polymorphisms (M235T, T174M) are associated with coronary heart disease in a Chinese population.J Renin Angiotensin Aldosterone Sys 2013; 14(4): 354–359.
• Konoshita T, Consortium GDO, Investigators Study. Do genetic variants of the renin–angiotensin system predict blood pressure response to renin–angiotensin system–blocking drugs? A systematic review of pharmacogenomics in the renin–angiotensin system. Curr Hypertens Rep 2011; 13(5): 356–36
• Jeunemaitre X, Soubrier F, Kotelevtsev YV, et al. Molecular basis of human hypertension: role of angiotensinogen. Cell 1992; 71(1):169–180.