Gastro-esophageal reflux and obstructive sleep apnea – is there a link?

• Authors: Piotr Pardak , Anna Pękala , Sara Jarmakiewicz , Rafał Filip
• Languages of publication: EN

Abstracts

EN

Introduction. The epidemic of obesity has led to an increase in the occurrence of obstructive sleep apnea and gastro-esophageal reflux disease. The mechanism of development of gastro-esophageal reflux disease is multifactorial, and studies conducted in the last decade have shed new light on the causes of its development in patients with sleep apnea and obesity. Aim. The aim of the study was to discuss the mechanism of development of gastro-esophageal reflux disease is multifactorial, and studies conducted in the last decade have shed new light on the causes of its development in patients with sleep apnea and obesity and the dysfunction of the lower esophageal sphincter. Material and methods. An analysis of literature regarding gastro-esophageal reflux and obstructive sleep apnea. Results. In obstructive sleep apnea and obesity, high levels of cytokines and insulin resistance are observed, resulting in disorders in the levels of ghrelin – a hormone responsible for normal gastrointestinal motility. Conclusion. The effect of deviations in the ghrelin profile on the development of gastro-esophageal reflux disease remains a matter for further research

Keywords

EN

gastro-esophageal reflux; ghrelin, obesity; obstructive sleep apnea

• Publisher: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
• Journal: European Journal of Clinical and Experimental Medicine
• Year: 2020
• Issue: 2
• Pages: 110-115

Contributors

author

Piotr Pardak

• Department of Gastroenterology with IBD Unit, Clinical Hospital No. 2, Rzeszów, Poland
• Medical College of Rzeszów University, Rzeszów, Poland

author

Anna Pękala

• Department of Gastroenterology with IBD Unit, Clinical Hospital No. 2, Rzeszów, Poland

author

Sara Jarmakiewicz

• Medical College of Rzeszów University, Rzeszów, Poland

author

Rafał Filip

• Department of Gastroenterology with IBD Unit, Clinical Hospital No. 2, Rzeszów, Poland
• Medical College of Rzeszów University, Rzeszów, Poland