An assessment of unstimulated salivary flow rate, IgA and clinical oral dryness among active and passive smokers

• Authors: Seeme Nigar , Sobia Hassan , Afsheen Maqsood , Naseer Ahmed , Mansour Al-Askar , Sameer A. Mokeem , Montaser N. Alqutub , Nada Aldahian , Eman I. AlSagob , Abdulrahman A. AlMubarak , Fahim Vohra , Tariq Abduljabbar

Abstracts

EN

ObjectivesThe aim of this study was to assess the impact of smoking on the whole salivary flow rate (SFR), IgA levels and clinical oral dryness (COD) among active and passive smokers.Material and MethodsThe participants were categorized as active smokers (N = 54) or passive smokers (N = 163). Saliva was collected in tubes and placed in ice storage at –70°C. Salivary IgA levels were assessed in duplication using the enzyme linked immunosorbent assay (ELISA) method. Following the saliva sample collection, the subjects were assessed for COD using the COD score, SFR and caries. Chi-square test, the t-test and ANOVA were employed to compare the clinical impact of the smoking status associated with specific variables (smoking status, number of cigarettes, active caries, gender, age, COD score, IgA level and SFR). A p-value of <0.05 was considered significant.ResultsTwo hundred and seventeen subjects with the mean age of 32.86±6.30 years, with 145 males (66.8%) and 72 females (33.2%), were included in the study. Among the active smokers, 88.8% were males compared to 11.2% females. The active smokers had the mean age of 32.52 years, a COD score of 1.43, an IgA level of 1.39 g/l, and a SFR of 0.37 ml/min. Among the passive smokers, 59.5% were males and 40.5% were females, with the mean age of 32.97 years, a COD score of 0.87 g/l, an IgA level of 1.47, and a SFR of 0.42 ml/min. Active caries showed a positive correlation with the number of cigarettes, with significance in the >35 years age group (p < 0.05).ConclusionsThe study demonstrated significant differences in SFR, IgA and COD scores among the active and passive smokers. The number of cigarettes had a negative impact on saliva production, IgA levels, the oral health status, and the progression of caries with respect to age and gender. Smoking potentially leads to xerostomia associated with active caries.

Keywords

EN

IgA; xerostomia; passive smokers; active smokers; salivary flow rate; oral dryness

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2021
• Volume: 35
• Issue: 1
• Pages: 39-51

Dates

published

2022

Contributors

author

Seeme Nigar

• Altamash Institute of Dental Medicine, Karachi, Pakistan (Department of Oral Pathology)

author

Sobia Hassan

• Altamash Institute of Dental Medicine, Karachi, Pakistan (Department of Pathology)

author

Afsheen Maqsood

• Bahria University Medical and Dental College, Karachi, Pakistan (Department of Oral Pathology)

author

Naseer Ahmed

• Altamash Institute of Dental Medicine, Karachi, Pakistan (Department of Prosthodontics)

author

Mansour Al-Askar

• King Saud University, Riyadh, Saudi Arabia (Department of Periodontics and Community Dentistry, College of Dentistry)

author

Sameer A. Mokeem

• King Saud University, Riyadh, Saudi Arabia (Department of Periodontics and Community Dentistry, College of Dentistry)

author

Montaser N. Alqutub

• King Saud University, Riyadh, Saudi Arabia (Department of Periodontics and Community Dentistry, College of Dentistry)

author

Nada Aldahian

• King Saud University, Riyadh, Saudi Arabia (Department of Restorative Dental Science, College of Dentistry)

author

Eman I. AlSagob

• Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia (Preventive Dental Sciences Department, Community Dentistry Division, College of Dentistry)

author

Abdulrahman A. AlMubarak

• King Saud University, Riyadh, Saudi Arabia (Department of Periodontics and Community Dentistry, College of Dentistry)

author

Fahim Vohra

• King Saud University, Riyadh, Saudi Arabia (Department of Prosthetic Dental Science, College of Dentistry)

author

Tariq Abduljabbar

• King Saud University, Riyadh, Saudi Arabia (Department of Prosthetic Dental Science, College of Dentistry)

Identifiers

DOI

10.13075/ijomeh.1896.01829

Biblioteka Nauki

2085673