Contribution of semiquantitative analysis with dynamic contrast enhanced magnetic resonance imaging to the differential diagnosis of focal liver lesions

• Authors: Hanife Gülden Düzkalır , Naciye Kış , Deniz Akay Urgun , Mehmet Oğuzhan Ağaçlı , Zeynep Gamze Kılıçoğlu

Abstracts

EN

Introduction and aim. We aimed to evaluate the usefulness of dynamic contrast-enhanced (DCE) MRI semiquantitative analysis values in focal liver lesions (FLL) to provide additional qualities that can be used in daily practice in the differential diagnosis of lesions. Material and methods. This retrospective study included 91 patients with liver masses on DCE-MRI. The sensitivity and specificity of time intensity curves (TIC) and semiquantitative analysis values were evaluated to differentiate benign and malignant lesions. Results. The study included 91 patients (376 lesions), aged between 28-81 years. Of the lesions, 303 were malignant and 73 were benign. In TIC semiquantitative analysis, it was found that “Tpeak” and “wash-out” rate values showed differences, especially in the differentiation of HCC, metastasis, and hemangioma. Area under curve, maximum relative enhancement, and “wash-in” and “wash-out” values of metastases and hemangiomas were different. Brevity of enhancement values of HSK, hemangiomas, and metastases were found to be different. The risk of malignancy was found to be high when the “wash-out” ratio was above 0.08 (sensitivity: 64.3%, specificity: 70.4%). Conclusion. We think that the 0.08 threshold value we found for the washout ratio with DCE-MRI semiquantitative analysis data will be useful in daily practice in the differentiation of malignant and benign FLL.

Keywords

EN

adult liver cancer; benign hepatoma; perfusion imaging

• Publisher: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
• Journal: European Journal of Clinical and Experimental Medicine
• Year: 2023
• Issue: 2
• Pages: 344-356

Dates

published

2023

Contributors

author

Hanife Gülden Düzkalır

• Kartal Dr. Lutfi Kirdar City Hospital, Department of Radiology, Istanbul, Turkey

author

Naciye Kış

• Department of Radiology, University of Medical Sciences, Prof Dr Cemil Tascıoglu City Hospital, İstanbul, Turkey

author

Deniz Akay Urgun

• Department of Radiology, University of California, USA

author

Mehmet Oğuzhan Ağaçlı

• Department of Radiology, University of Medical Sciences, Umraniye Education and Research Hospital, İstanbul, Turkey

author

Zeynep Gamze Kılıçoğlu

• Department of Radiology, University of Medical Sciences, Haydarpaşa Education and Research Hospital, İstanbul, Turkey

Identifiers

DOI

10.15584/ejcem.2023.2.6

Biblioteka Nauki

25102539