Salivary microbial diversity – an investigation on possible biomarkers for polycystic ovarian syndrome from eastern India

• Authors: Kusum Ghosh , Shreyoshi Chakraborty , Diptendu Chatterjee , Arup Ratan Bandyopadhyay

Abstracts

EN

Introduction and aim. Polycystic ovarian syndrome (PCOS) is one of the major reproductive health issues, thought to be multifactorial, needs serious attention as a dual burden (health and economic) mainly for developing countries like India, due to its rapid rise (30%) in the last couple of years. Therefore, widespread and liberal screening for this disorder towards prognosis, diagnosis and intervention seems to be an urgent area of research. In this background, the present study attempts to unravel the association of salivary microbial diversity and PCOS. Material and methods. To achieve the purpose 100 clinically diagnosed PCOS individuals and 110 age matched non-PCOS participants from Bengalee Hindu caste population, West Bengal, India was considered. Obtained salivary samples were identified with 16S rDNA amplification and microbial diversity were determined by Alu I restriction enzyme digestion. Results. The present study revealed an explicit pattern of DNA fragment lengths varied between 200 bp and 225 bp in PCOs in comparison to the non-PCOS group. Conclusion. The cardinal feature of the present study as the first attempt from India envisaged, utilization of salivary microbial diversity as an additional potential and economizing biomarker for PCOS that stimulate new horizon of research in 21st century’s anthropology – the anthropology of microbes.

Keywords

EN

diagnostic biomarker; PCOS; reproductive health; salivary microbiome; well-being

• Publisher: Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
• Journal: European Journal of Clinical and Experimental Medicine
• Year: 2023
• Issue: 4
• Pages: 736-741

Dates

published

2023

Contributors

author

Kusum Ghosh

• Department of Anthropology, University of Calcutta, Kolkata, India

author

Shreyoshi Chakraborty

• Center for Liver Research, School of Digestive and Liver Diseases, IPGME & R, Kolkata, India

author

Diptendu Chatterjee

• Department of Anthropology, University of Calcutta, Kolkata, India

author

Arup Ratan Bandyopadhyay

• Department of Anthropology, University of Calcutta, Kolkata, India

Identifiers

DOI

10.15584/ejcem.2023.4.12

Biblioteka Nauki

29520460