Cancer incidence in Czech black coal miners in association with coalworkers’ pneumoconiosis

• Authors: Hana Tomaskova , Zdenek Jirak , Anna Splichalova , Pavel Urban

Abstracts

EN

Objective: The aim of the study was comparison of cancer incidence risk of lungs, stomach, colon, bladder and kidneys from ex-miners of black coal mines and the general male population of the Czech Republic. Materials and methods: The analysis was conducted in two cohorts of ex-miners according to the presence of coalworkers’ pneumoconiosis (CWP). The first cohort included the miners without CWP (N = 6705), and the second cohort included the miners who were compensated for CWP (N = 2158). Personal and occupational data was merged with the data in the National Population Register and the National Oncological Register for the period from 1992 to 2006. Cancer risk in miners in comparison to the general male population of the Czech Republic was evaluated by SIR (Standardized Incidence Ratio) and 95% confidence interval (CI). Results: About twice as high risk of lung cancer was found in miners with CWP (SIR = 2.21; 95% CI: 1.75–2.76). Lung cancer risk correlated with the severity of CWP (simple CWP SIR=1.96; 95% CI: 1.48–2.56, progressive massive fibrosis SIR = 4.29; 95% CI: 2.09–7.87). No increased risk of lung cancer was found in ex-miners without CWP. The risk of malignant neoplasm at the other selected sites was comparable with the risk in the general male population of the Czech Republic. Conclusions: This study found increased lung cancer risk in coal miners with CWP, but not in those without CWP, comparing with the general population. These results served as the basis for the inclusion of lung cancer in association with CWP into a new Czech list of occupational diseases.

Keywords

EN

lung cancer; coalworkers’ pneumoconiosis; black coal miners; silica; cancer incidence

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2012
• Volume: 25
• Issue: 2
• Pages: 137-144

Dates

published

2012

Contributors

author

Hana Tomaskova

• Faculty of Medicine, Department of Epidemiology and Public Health, University of Ostrava, Ostrava Zabreh, Czech Republic
• Institute of Public Health in Ostrava, Ostrava, Czech Republic

author

Zdenek Jirak

• Faculty of Medicine, Institute of Physiology and Pathophysiology, University of Ostrava, Ostrava Zabreh, Czech Republic

author

Anna Splichalova

• Faculty of Medicine, Department of Epidemiology and Public Health, University of Ostrava, Ostrava Zabreh, Czech Republic
• Institute of Public Health in Ostrava, Ostrava, Czech Republic

author

Pavel Urban

• National Institute of Public Health, Prague, Czech Republic

Identifiers

DOI

10.2478/S13382-012-0015-9

Biblioteka Nauki

2180096