Polish mother and child cohort study (REPRO_PL) - Methodology of follow-up of the children

• Authors: Kinga Polańska , Wojciech Hanke , Joanna Jurewicz , Wojciech Sobala , Christian Madsen , Per Nafstad , Per Magnus

Abstracts

EN

Background: A prospective cohort study design gives the opportunity for identifi cation, update of different exposures and their verifi cation by biomarker measurements. The aim of The Polish Mother and Child Cohort Study (REPRO_PL) is to evaluate the impact of exposure to different environmental factors during pregnancy and, after birth, on the pregnancy outcome, children’s health and neurodevelopment. Materials and Methods: REPRO_PL cohort was established in 2007. From the cohort of 1300 mother-child pairs, 300 children are followed-up until they are two years old to asses the exposure, health status and neurodevelopment. Children are examined twice: at one and two years of age by a pediatrician and a psychologist/child development specialist. During each visit, detailed questionnaire is conducted with the mothers and supplemented with the information from the medical charts to have appropriate recognition of the child’s health and development. Additionally, the current health status of the child is checked and his/her biometry is performed. A urine sample is collected from each child for the verifi cation of environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbons (PAH) exposure. Some children have a blood sample collected for the assessment of the lead and cadmium levels. Child’s neurodevelopment is assessed based on Bayley Scales for Infant and Toddler Development (Bayley-III). Results and Conclusions: The results of the study will become available within the next few years and will help to determine the impact of the environmental exposures on children’s health and neurodevelopment. REPRO_PL cohort is a middle-sized cohort, very much focused on specific research questions with the potential for future extension and cooperation.

Keywords

EN

birth cohort; follow-up of children; child’s health; neurodevelopment

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2011
• Volume: 24
• Issue: 4
• Pages: 391-398

Dates

published

2011

Contributors

author

Kinga Polańska

• Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland

author

Wojciech Hanke

• Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland

author

Joanna Jurewicz

• Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland

author

Wojciech Sobala

• Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland

author

Christian Madsen

• Division of Epidemiology, The Norwegian Institute of Public Health, Oslo, Norway

author

Per Nafstad

• Department of General Practice and Community Medicine, The University of Oslo, Oslo, Norway

author

Per Magnus

• Division of Epidemiology, The Norwegian Institute of Public Health, Oslo, Norway

Identifiers

DOI

10.2478/s13382-011-0026-y

Biblioteka Nauki

2185377