Management of a patient with thermal burns and para-chloronitrobenzene poisoning

• Authors: Yuanhai Zhang , Xingang Wang , Liangfang Ni , Ruiming Jiang , Liping Liu , Chunjiang Ye , Chunmao Han

Abstracts

EN

Para-chloronitrobenzene (p-CNB), a hazardous and toxic substance, is widely used as an intermediary in chemical industries. p-CNB can cause methaemoglobinaemia due to electron-withdrawing properties of the nitro and chlorine groups. We present a case of a 23-year-old man suffering from thermal burns and p-CNB poisoning. In this case, severe methaemoglobinaemia was caused by the absorption of p-CNB through the burn wounds. Despite active treatment, such as the antidote of methylene blue, the patient’s methaemoglobinaemia progressed, with slowly increasing methaemoglobin (MetHb) level. This case highlights the complexity and difficulty of managing this type of injury. To our knowledge, this case can be the first case report describing methaemoglobinaemia induced by p-CNB in a patient with thermal burns.

Keywords

EN

chemical burns; methaemoglobinaemia; Methylene Blue; para-chloronitrobenzene

• Publisher: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
• Journal: International Journal of Occupational Medicine and Environmental Health
• Year: 2014
• Volume: 27
• Issue: 5
• Pages: 882-887

Dates

published

2014

Contributors

author

Yuanhai Zhang

• Department of Burn and Plastic Surgery, Zhejiang Quhua Hospital, Quzhou, China

author

Xingang Wang

• College of Medicine, Department of Burns & Wound Care Centre, 2nd Affiliated Hospital of Zhejiang University, Hangzhou, China

author

Liangfang Ni

• Department of Burn and Plastic Surgery, Zhejiang Quhua Hospital, Quzhou, China

author

Ruiming Jiang

• Department of Burn and Plastic Surgery, Zhejiang Quhua Hospital, Quzhou, China

author

Liping Liu

• Department of Burn and Plastic Surgery, Zhejiang Quhua Hospital, Quzhou, China

author

Chunjiang Ye

• Department of Burn and Plastic Surgery, Zhejiang Quhua Hospital, Quzhou, China

author

Chunmao Han

• College of Medicine, Department of Burns & Wound Care Centre, 2nd Affiliated Hospital of Zhejiang University, Hangzhou, China

Identifiers

DOI

10.2478/s13382-014-0309-1

Biblioteka Nauki

2178908