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2018 |

Article title

Does benzo[a]pyrene affect the heart embryonic development?

Content

Title variants

Languages of publication

EN

Abstracts

EN
Benzo[a]pyrene is a polycyclic aromatic hydrocarbon of well proved toxic effect on animal cells and tissues. We used chicken in ovo developmental model to verify its influence on selected parameters of the heart rhythm and on the antioxidative defense in the heart tissue. We determined that the dose of 1 mg/kg weight of eggs of benzo[a]pyrene strongly activates the glutathione-dependent antioxidative system, but it do not significantly affect the heart conducting system of the chicken embryo. We postulate that further study on the benzo[a]pyrene action during embryonic development of birds is recommended.

Keywords

EN
benzo[a]pyrene   ecg   embryo   GSH   heart   MDA  

Contributors

  • Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
author
  • Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland

References

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  • Batoryna, M., Lis, M.W., Formicki, G. (2018). Antioxidant defense in the brain of 1-d-old chickens exposed in ovo to acrylamide. British Poultry Science, 59(2), 198–204. https://doi.org/10.1080/00071668.2017.1415427
  • Davey, M.G., Tickle, C. (2007). The chicken as a model for embryonic development. Cytogenetic and Genome Research, 117, 231–239. https://doi.org/10.1159/000103184
  • European Environment Agency (2016). Air quality in Europe - 2016 report, EEA Report No 28/2016. Publications Office of the European Union, Luxembourg.
  • Le Douarin, N.M. (1998). Les chimères de caille et de poulet pour étudier l’embryogenèse. Pour la Science, 252, 46–54. [In French]
  • Lee, B.M., Shim, G.A. (2007). Dietary exposure estimation of benzo[a]pyrene and cancer risk assessment. Journal of Toxicology and Environmental Health, Part A, 70(15–16), 1391–1394. https://doi.org/10.1080/15287390701434182
  • Pardanaud, L., Moyon, D., Eichmann, A. (2001). L’embryologie des vaisseaux. Médecine sciences, 5(17), 543–551. [In French]
  • Tazawa, H., Watanabe, W., Burggren, W.W. (1994). Embryonic heart rate in altricial birds, the Pigeon (Columba domestica) and the Bank Swallow (Riparia riparia). Physiological Zoology, 67(6), 1448–1460.
  • Yoshiyama, Y., Kanke, M. (2005). Toxic interactions between fluconazole and disopyramide in chick embryos. Biological and Pharmaceutical Bulletin, 28(1), 151–153. https://doi.org/10.1248/bpb.28.151

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.ojs-doi-10_24917_25438832_3supp_4
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