Drug susceptibility and enzymatic activity of Candida isolated from mobile phone and hand surfaces

• Authors: Kordecka, A , Krajewska-Kułak, E , Łukaszuk, C , Kraszyński, M , Kraszyńska, B

Abstracts

EN

Introduction: Evaluation of susceptibility of isolated fungi as well as the type and activity of enzymes they release allows to determine their pathogenicity. Purpose; To assess potential correlations between drug susceptibility and enzymatic activity of strains isolated from mobile phone and hand surfaces Materials and methods: The mycological evaluation included 175 mobile phones and 175 hands of the phone owners. Drug susceptibility was assessed using the FUNGITEST; enzymatic activity was evaluated using the API ZYM test. Results: We found significant correlations between an increased resistance to 5-fluorocytosine, ketoconazole, fluconazole and higher activity of six selected enzymes for Candida glabrata strains isolated from hand surfaces. We found also significant correlations between an increased resistance to 5-fluorocytosine, ketoconazole, miconazole, itraconazole and higher activity of six selected enzymes for Candida albicans strains isolated from hand surfaces. We found significant correlations between an increased resistance to 5fluorocytosine, ketoconazole, itraconazole, fluconazole and higher activity of six selected enzymes for Candida krusei strains isolated from hand surfaces as well as an increased resistance to 5-fluorocytosine, ketoconazole, itraconazole, fluconazole and higher activity of five selected enzymes for strains isolated from phone surfaces. Conclusions: We found varying correlations between enzymatic activity and drug resistance depending on the site of isolation and the species/genus of fungi. The drugs to which the evaluated strains showed resistance were the same for hand and mobile phone isolates.

Keywords

EN

Keywords: Candida; Fungitest; API ZYM; hands; mobile telephones

• Publisher: Uniwersytet Medyczny w Białymstoku
• Journal: Progress in Health Sciences
• Year: 2017
• Volume: 7(2)
• Pages: 7-18

Dates

published

2017-11-12

Contributors

author

Kordecka, A

author

Krajewska-Kułak, E

author

Łukaszuk, C

author

Kraszyński, M

author

Kraszyńska, B

Identifiers

DOI

10.5604/01.3001.0010.5716