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Cardiotoxic effect due to accidental ingestion of an organic solvent

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Cieślik-Guerra U. I., Rechciński T., Trzos E., Wierzbowska-Drabik K., Uznańska-Loch B., Winnicka R., Krakowiak A., Kasprzak J. D., Fröhlich C., Kurpesa M.

International Journal of Occupational Medicine and Environmental Health

2015

vol. 28

issue 1

174-179

Toxic myocardial injury can be misdiagnosed as a myocardial infarction, resulting in the patient undergoing standard treatment for cardiac rehabilitation. However, such inadequate therapeutic strategies can lead to cardiovascular complications including dilated cardiomyopathy. This study presents a case of a 65-year-old man after accidental ingestion of organic solvents (toluene and xylene), whose condition demonstrated all the criteria for diagnosis of myocardial infarction. The qualitative determinations of the above mentioned volatile organic compounds (VOCs) in whole blood were carried out using a headspace sampling by means of gas chromatography. Cardiac catheterization revealed no specific coronary lesions, only a muscular bridge causing a 30–50% stenosis in the middle of the circumflex branch of the left coronary artery.

Evaluation of the impact of atmospheric pressure in different seasons on blood pressure in patients with arterial hypertension

81%

Kamiński M., Cieślik-Guerra U. I., Kotas R., Mazur P., Marańda W., Piotrowicz M., Sakowicz B., Napieralski A., Trzos E., Uznańska-Loch B., Rechciński T., Kurpesa M.

International Journal of Occupational Medicine and Environmental Health

2016

vol. 29

issue 5

783-792

Objectives Atmospheric pressure is the most objective weather factor because regardless of if outdoors or indoors it affects all objects in the same way. The majority of previous studies have used the average daily values of atmospheric pressure in a bioclimatic analysis and have found no correlation with blood pressure changes. The main objective of our research was to assess the relationship between atmospheric pressure recorded with a frequency of 1 measurement per minute and the results of 24-h blood pressure monitoring in patients with treated hypertension in different seasons in the moderate climate of the City of Łódź (Poland). Material and Methods The study group consisted of 1662 patients, divided into 2 equal groups (due to a lower and higher average value of atmospheric pressure). Comparisons between blood pressure values in the 2 groups were performed using the Mann-Whitney U test. Results We observed a significant difference in blood pressure recorded during the lower and higher range of atmospheric pressure: on the days of the spring months systolic (p = 0.043) and diastolic (p = 0.005) blood pressure, and at nights of the winter months systolic blood pressure (p = 0.013). Conclusions A significant inverse relationship between atmospheric pressure and blood pressure during the spring days and, only for systolic blood pressure, during winter nights was observed. Int J Occup Med Environ Health 2016;29(5):783–792

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2 International Journal of Occupational Medicine and Environmental Health

2 Cieślik-Guerra U. I.

2 Kurpesa M.

2 Rechciński T.

2 Trzos E.

2 Uznańska-Loch B.

1 Fröhlich C.

1 Kamiński M.

1 Kasprzak J. D.

1 Kotas R.

1 Krakowiak A.

1 Marańda W.

1 Mazur P.

1 Napieralski A.

1 Piotrowicz M.

1 Sakowicz B.

1 Wierzbowska-Drabik K.

1 Winnicka R.

1 2016

1 2015

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Cardiotoxic effect due to accidental ingestion of an organic solvent

Evaluation of the impact of atmospheric pressure in different seasons on blood pressure in patients with arterial hypertension