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1
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Rat skin as an experimental model in medicine

100%
Niczyporuk M.
Progress in Health Sciences
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2018
|
vol. 8(2)
223-228
EN
Scientific experiments due to safety and ethical limitations regarding research human are often based on animal models. Rats are laboratory animals which are commonly used for these purposes. It should be remembered that morphologi- cal and functional differences between rat skin and human skin may refer to the correct interpretation of scientific results.
2
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The knowledge of beauty salon clients about hallux valgus therapy. Preliminary study

51%
Niczyporuk M., Pupek P., Masłowska J., Knaś M.
Progress in Health Sciences
|
2019
|
vol. 1
65-69
EN
Introduction: Hallux valgus is a frequent painful deformity of the feet, and occurs most often in women of different ages. People with hallux valgus have, among others, a genetic predisposition, a weaker ligament-and joint structure of the foot, pes planus (flatfoot), rheumatoid arthritis, muscular balance disorders, are obese, and wear improper footwear. Purpose: To assess the knowledge of beauty salon clients on the subject of professional care of hallux valgus. Materials and methods: Research was conducted in a beauty salon in Lomza, Poland using an original questionnaire. The study was approved (No. 4/2013) by the senate of the Ethics Committee of the Lomza State University of Applied Sciences. Results: The conducted research showed that 48% of the surveyed women dealt with hallux valgus using orthopedic insoles, and 26% underwent procedures recommended by a specialist. Respondents knew kinesiotherapy and taping as treatment methods for this ailment. The vast majority of the surveyed women would undergo non-surgical hallux valgus treatment, and only a few would opt for surgery. Conclusions: The knowledge of the studied women about hallux valgus was quite extensive.
3
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Analysis of students’ knowledge about the biological hazards present in the work of cosmetologist

51%
Niczyporuk M., Juśkiewicz I., Knaś M.
Progress in Health Sciences
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2018
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vol. 8(2)
131-136
EN
Introduction: The cosmetologists' health complications can be inducted by their work conductors. The presence of numerous biological harmful factors in their future workplace requires from graduates the faculty of cosmetology extensive knowledge about health threats and prevention methods. Purpose: The survey aimed to get to know and compare the knowledge of students of the first and third year of Cosmetology at the Lomza State University of Applied Sciences on the biological hazards present in cosmetologist's work. Materials and methods: 50 female students (24 first-year students and 26 third-year students) took part in the survey. Results: In almost all cases, responses from third- year Cosmetology showed a higher level of knowledge of biological infections which may threaten in the beauty parlor for themselves and their clients. Also, in the area of preventing the spread of these infections, they had a higher knowledge than their younger friends. Conclusions: The level of knowledge of third-year students is significantly higher than the knowledge of first-year students in Lomza State University of Applied Sciences. It is satisfactory that first-year students who already started education in this field, they know biological threats.
4
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Effect of a high amino acid diet on antioxidant barrier parameters of rat skin.

51%
Niczyporuk M., Knaś M., Grądzka K., Car H.
Progress in Health Sciences
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2019
|
vol. 1
45-50
EN
Introduction: Oxidative stress is largely responsible for numerous skin complications that occur in the course of various diseases as well as accelerated skin aging. A high amino acid diet, supplemented with whey protein concentrate (WPC), is well-balanced and has well-absorbing proteins, which are an ideal source of essential amino acids. Purpose: To assess what changes will occur in the antioxidant barrier of unharmed skin of rats on a high amino acid diet. Materials and methods: The study was conducted on sexually mature male Wistar rats (160-180g): 1. control (standard feed), 2. high amino acid diet (WPC-80 80% whey protein) administered for 7 days at a dose of 0.3g/kg of body weight, 3. WPC-80 for 7 days at a dose of 0.5g/kg of body weight, 4. WPC-80 for 14 days at a dose of 0.3g/kg of body weight, 5. WPC-80 for 14 days at a dose of 0.5g/kg of body weight. Total antioxidant capacity, total oxidative status and oxidative stress index were determined. Results: Enrichment of a standard diet with WPC-80 did not affect the total oxidative status of undamaged healthy rat skin. This study shows that a diet rich in amino acids in rats caused an increase in total antioxidant capacity, but statistically significant values were obtained after 14 days of administering WPC at a dose of 0.5mg/kg of body weight. Conclusions: Enrichment of a standard diet with WPC-80 strengthens the antioxidant barrier in unwounded healthy rat skin.
5
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Lipodystrophy as dietary and cosmetic problem

51%
Niczyporuk M., Bacisz Ł., Jankowska B., Knaś M.
Progress in Health Sciences
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2019
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vol. 1
60-64
EN
Introduction: Lipodystrophy is a skin composition disorder. One of the kinds of lipodystrophy is cellulite. Differences in fat tissue composition between woman and man are the cause that lipodystrophy affects women more often. It affects women of different ages - from maturation to menopause. Is estimated that this problem affects 85% of women above the age of 20. Purpose: To analyse the impact of cosmetic procedures and diets on skin affected by cellulite. Materials and methods: The study was conducted based on a survey using a proprietary questionnaire filled by 57 clients of beauty salon Health and Beauty Center “Anamed”, located in Lomza. The study was conducted between 12.2014 and 01.2015. Results: The diet and treatments performed by the respondents were analyzed and their subjective effectiveness assessed. After analyzing the data, it was observed that one-way actions do not bring the expected results. In order to reduce cellulite, it is necessary to undertake multidirectional activities. Conclusions: Cosmetic treatments minimize cellulite changes and improve the overall condition of the skin. Proper healthy eating habits should be promoted because they help to act in the treatment and more importantly preventive in the formation of cellulite.
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Effect of a high amino acid diet on antioxidant barrier parameters of rat skin. Part 2

51%
Knaś M., Niczyporuk M., Grądzka K., Car H.
Progress in Health Sciences
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2019
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vol. 1
70-75
EN
Purpose: The imbalance between the formation of reactive oxygen species and antioxidant capacity of the body is known as oxidative stress. Exposition of the skin to free radicals, the origin of the internal and external causes activation of multiple mechanisms to eliminate them and prevent in this way the development of oxidative stress. The aim of this experiment was examining what changes are taking place in the antioxidant barrier of unwounded healthy skin of rats, who are on a high amino acids diet for 7 and 14 days at administered doses of 0.3 and 0.5 g/kg body weight. Materials and Methods: The study was performed on male Wistar rats divided into 5 groups: 1. control (standard feed), 2. high amino acid diet (WPC-80 80% whey protein) administered for 7 days at a dose of 0.3g/kg of body weight, 3. WPC-80 for 7 days at a dose of 0.5g/kg of body weight, 4. WPC-80 for 14 days at a dose of 0.3g/kg of body weight, 5. WPC-80 for 14 days at a dose of 0.5g/kg of body weight. The concentration of superoxide dismutase 2 and 3, the concentration of catalase specific activity of glutathione peroxidase, the concentration of glutathione and total protein content were determined. Results: The supplementation of the standard diet by the preparation of WPC-80 administered in a dose 0.5 g/kg body weight for 14 days containing methionine and cysteine (essential amino acids involved in the formation of glutathione), significantly increases the concentration of reduced glutathione. Conclusions: Enrichment of a standard diet with WPC-80 caused by the significant increases of non-enzymatic antioxidant.
7
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Evaluation of the quality of life of patients with osteoarthritis

45%
Niczyporuk M., Kłossowska J., Kleszczewska E., Shpakou A., Knaś M.
Progress in Health Sciences
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2018
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vol. 8(2)
1-9
EN
Purpose: The tools for measuring objective quality of life include research regarding the conditions of a successful life and life satisfaction. Osteoarthritis (OA) is characterized by progressive degradation and loss of articular cartilage as well as abnormal bone growth and remodeling, located directly under the cartilage. The aim of this study is to answer the question on which level OA patients perceive their quality of life dependent on health. Material and methods: The Polish version of the HAQ questionnaire, assessing the quality of life over the past week, was used for overall assessment of quality of life. The Polish version of the AIMS-2 questionnaire was used as a specific questionnaire for assessing the health status of patients with osteoarthritis. Surveys were conducted in a group of 240 people. Results: The quality of life dependent on health is significantly reduced in the group of healthy people who take painkillers sporadically because of other reasons and in the OA pateints group compared to the control group, the same as in the OA pateints group compared to the group of healthy people who take painkillers sporadically for other reasons. Conclusions: According to the answers from the questionnaire, patients with OA seek different forms of improving their quality of life. It is important to change their lifestyle (weight reduction, using a bench-mounted bike, walking stick or walking frame), reducing the surface area of the joints, reducing the defective position of the limb axis. Exercises that increase muscle mass and exercises to improve joint mobility should be introduced. It is advisable to refer the OA patient for physical therapy and/or balneotherapy.
8
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Quality of life of osteoarthritis patients in the aspect of analgesic treatment

45%
Niczyporuk M., Kłossowska J., Kleszczewska E., Shpakou A., Knaś M.
Progress in Health Sciences
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2019
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vol. 1
36-44
EN
Introduction: Osteoarthritis an inflammatory process in the synovial membrane. These changes cause pain and joint deformities. Pharmacists can assess patients’ quality of life, which can be a good criterion for assessing analgesics treatment effectiveness and prevent the growing phenomenon of polypharmacy and self-treatment. Purpose: To answer these questions: 1) Is there a relationship between the quality of life of patients with osteoarthritis taking analgesics and those with osteoarthritis taking analgesics and implemented rehabilitation? 2) Do patients using analgesics practice polypharmacy? 3) Are patients with osteoarthritis the main consumers of painkillers? and 4) Does the use of analgesics affect the health-related quality of life of patients with osteoarthritis? Materials and methods: The study was conducted on 240 people who were divided into three groups: osteoarthritis, reference (generally healthy, occasionally taking analgesics), and control (generally healthy, no intake of analgesics). To assess the rise in analgesics consumption by patients with osteoarthritis and the phenomenon of polypharmacy, an original questionnaire was used. Results: There is a relationship between the quality of life of patients with osteoarthritis taking analgesics. Statistical analysis showed that in the years 2013-2015 the purchase of prescription analgesics and without a prescription systematically, significantly increased. Conclusions: Patients using analgesics unknowingly practice polypharmacy. In Ars Medica Pharmacies, analgesics purchases by patients with osteoarthritis grew significantly in the analyzed period, but they are not the main analgesics consumers. Use of analgesics by patients with osteoarthritis improves their health-related quality of life.
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