The article examines the main directions, which can increase synergistic effects of ecological and economic systems in the transition to information economy and the use of information and communication technologies. It reveals the synergistic approach which investigates conditions for improvement ecological and economic systems efficiency. It shows the most effective forms of factors and the interaction of these systems. The article suggests the mechanisms of harmonization the relations according to which economic agents interact in ecological and economic systems in order to increase their effective existence and mutual interaction. The necessity of taking into account the synergistic phenomenon in making economic decisions that somehow can “soften” the action of “hard” laws by which the interaction of environmental and natural systems occurs, and improve the efficiency of their operation, which in turn would make management decisions to solving environmental and economic problems.
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