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In the article, from the standpoint of the content of the concept of "green" economy and eco-innovation, it is concluded the need to create regional innovation system focused on achieving the goals of the green development of the region. It is emphasized the need to define a strategic vector of development of the region basing on the determination of the most important socio-ecological-economic problems of the region and assessment of its capacity to implement eco-innovations. There are proposed the directions of diagnostic of eco-innovation potential of the region based on assessment of environmental friendliness of its components: market, research, production and infrastructure, institutional. Depending on the level of capacity to implement environmentally-oriented innovation in the region (low, medium, high) it is proposed to use such strategies of regional development: adaptation of innovative processes in terms of "green" economy; the development of models of "green" production and consumption in some sectors of the regional economic complex; the strategy of "green" sustainable development of the region. The necessity of changing the organizational forms of realization of the process of institutional management of innovations: the formation of the partnership model of interaction with the business, as well as the promotion of grassroots innovation in the most important areas of social development.
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