Full-text resources of CEJSH and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

Results found: 4

first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  chemicals
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Publication available in full text mode
Content available

Rules and recent trends for setting health-based occupational exposure limits for chemicals

100%
Skowroń J., Czerczak S.
International Journal of Occupational Medicine and Environmental Health
|
2015
|
vol. 28
|
issue 2
243-252
EN
The working environment is the special case of the non-natural environment created by man in which the increased production activity brings about the concentration of stimulators particularly aggressive to the human organism, such as chemical hazards, noise, vibration, extreme temperatures, and finally, intensified psychological and emotional stress. Depending on the nature and intensity, working environment factors have been classified into dangerous, harmful and annoying. The workers are more and more frequently exposed to dangerous chemicals in the working environment. The chemicals cause many diseases including, in the 1st place, respiratory insufficiency, inflammatory skin conditions, psychoneurological disorders and neoplastic diseases. Occupational exposure limit values (OELs), the main criteria for occupational exposure assessment, constitute an important factor for the safe use of chemicals in the working environment. In Poland, to date there are 524 chemical substances and 19 dusts for which maximum admissible concentrations (MAC) have been established.
2
Publication available in full text mode
Content available

Review of current evidence on the impact of pesticides, polychlorinated biphenyls and selected metals on attention deficit / hyperactivity disorder in children

100%
Polańska K., Jurewicz J., Hanke W.
International Journal of Occupational Medicine and Environmental Health
|
2013
|
vol. 26
|
issue 1
16-38
EN
The aim of this review was to investigate the association between attention defi cit / hyperactivity disorder (ADHD) or ADHD- related symptoms and industrial chemicals, such as organophosphates and organochlorine pesticides, polychlorinated biphenyls (PCBs), lead, mercury and manganese. Medline, PubMed and EBSCO searches were performed to identify the studies that analyzed the association of prenatal and postnatal child exposure to such toxicants and ADHD or ADHD-related symptoms. The review is restricted to human studies published in English in peer-reviewed journals since 2000. Most of the presented studies focused on pesticides, PCB and lead. The impact of mercury and manganese was investigated less frequently. The fi ndings indicate that children’s exposure to organophosphate pesticides may cause symptoms consistent with pervasive developmental disorder, ADHD or attention problems. Exposures to organochlorine pesticides and PCBs were associated with ADHD-like behaviors such as alertness, quality of alert response, and cost of attention. The studies provided evidence that blood lead level below 10 μg/dl was associated with ADHD or ADHD-related symptoms. Information on the association between exposure to mercury and neurotoxicity is limited, and requires further confi rmation in future research. Two studies indicated that exposure to manganese is related to ADHD; such exposure and its impact on children neurodevelopment need to be further investigated. Future studies should use a prospective design with multiple biological samples collected over time for better assessment of exposure and its critical windows. Additionally, inclusion of potential confounding factors and co-exposures is crucial.
3
Publication available in full text mode
Content available

Health risk in road transport workers. Part I. Occupational exposure to chemicals, biomarkers of effect

86%
Gromadzińska J., Wąsowicz W.
International Journal of Occupational Medicine and Environmental Health
|
2019
|
vol. 32
|
issue 3
267-280
EN
Motor vehicle emissions constitute a mixture of different chemicals: volatile organic solvents, polycyclic aromatic hydrocarbons, heavy metals, isocyanates, etc. Drivers working in car cabins are exposed to chemicals deriving from incomplete combustion of fuels, exhaust emissions from working engines and fuel evaporation. Concentrations of these substances are rather low and do not exceed the applicable hygiene standards, but some of them pose, or are suspected to pose, carcinogenic risk. The interaction of chemical substances with human cells and tissues can lead to a number of modifications of metabolic pathways at a cellular level. The first biological mechanism of metabolic modulation is an inflammatory state and oxidative stress generation. The aim of this review is to analyze biomarkers of effect and to assess the hazard of occupational exposure of drivers. Int J Occup Med Environ Health. 2019;32(3):267–80
4
Publication available in full text mode
Content available

A scoping survey of attitudes towards occupational exposure limits and REACH derived no effect levels for workers among chemical risk managers at Swedish workplaces

86%
Schenk L.
International Journal of Occupational Medicine and Environmental Health
|
2020
|
vol. 33
|
issue 5
611-620
EN
ObjectivesSetting and implementing occupational exposure limits (OELs) is one of the measures taken to protect workers from adverse effects of hazardous chemicals. The EU Regulation on Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) introduced an additional kind of exposure guidance values for workers; namely, the derived no effect level (DNEL) for workers’ inhalation exposure (worker DNEL). About 500 substances have a Swedish OEL, while roughly 5000 substances have a worker DNEL derived by REACH registrants. This work aims to investigate how the Swedish OELs and worker DNELs are perceived at Swedish workplaces, and whether worker DNELs are considered a possible alternative to OELs when the latter are lacking.Material and MethodsAn online questionnaire was designed and sent to Swedish companies identified through the European Chemicals Agency’s database of registered substances (N = 126) and the Swedish Chemicals Agency’s registry of companies that import or manufacture notifiable chemical products (N = 227). The response rates were 52% and 38%, respectively.ResultsThe respondents stated that they were using the Swedish OELs and most of them considered these to be a suitable risk management tool. As about one-third of the respondents expressed that they had some experience in using substances without the Swedish OELs, there are certain data gaps that worker DNELs may fill. One-third of the respondents familiar with worker DNELs stated that they would consider using worker DNELs for substances without the Swedish OELs. However, nearly half of the respondents reported to be unfamiliar with worker DNELs.ConclusionsPoor familiarity with DNELs may pose an obstacle to properly recognizing DNELs’ potential as well as the possible limitations of individual DNELs. There is a need for education about DNELs, as well as for tools facilitating the evaluation of DNELs and OELs from other sources in cases where the applicable Swedish OEL is lacking.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.