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1

Effects of exposure to electromagnetic field radiation (EMFR) generated by activated mobile phones on fasting blood glucose

100%

Meo S. A., Al Rubeaan K.

International Journal of Occupational Medicine and Environmental Health

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2013

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vol. 26

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issue 2

235-241

EN

Objective: Extensive use of mobile phones has been accompanied by a common public debate about possible adverse effects on human health. No study has been published so far to establish any association between the fastest growing innovation of mobile phone and fasting blood glucose. The aim was to determine the effects of exposure to electromagnetic field radiation generated by mobile phones on fasting blood glucose in Wistar Albino rats. Materials and Methods: 40 Male Albino rats (Wistar Strain) were divided into 5 equally numerous groups. Group A served as the control one, group B received mobile phone radiation for less than 15 min/day, group C: 15-30 min/day, group D: 31-45 min/day, and group E: 46-60 min/day for a total period of 3 months. Fasting blood glucose was determined by using Spectrophotometer and serum insulin by Enzyme-linked Immunosorbent Assay (ELISA). The Homeostatic Model (HOMA-B) was applied for the assessment of β-cell function and (HOMA-IR) for resistance to insulin. Results: Wister Albino rats exposed to mobile phone radiation for longer than 15 min a day for a total period of 3 months had significantly higher fasting blood glucose (p < 0.015) and serum insulin (p < 0.01) compared to the control group. HOMA-IR for insulin resistance was significantly increased (p < 0.003) in the groups that were exposed for 15-30 and 46-60 min/day compared to the control rats. Conclusion: The results of the present study show an association between long-term exposure to activated mobile phones and increase in fasting blood glucose and serum insulin in Albino rats.

2

Prevention and nutritional therapy of metabolic syndrome

88%

Rożniata M., Zujko K., Zujko, M.E

Progress in Health Sciences

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2017

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vol. 7(2)

100-104

EN

The term metabolic syndrome (MetS) defines the cooccurrence of the related risk factors of metabolic origin that promote the development of cardiovascular diseases with atherosclerotic background and type 2 diabetes. The diagnostic criteria of MetS have undergone modifications for years. Until now no clear definition of MetS has been established. The latest diagnostic criteria of MetS published in 2009 by a group of IDF (International Diabetes Federation) and AHA/NHLBI (American Heart Association/ National Heart, Lung and Blood Institute) experts discern three out of five risk factors: abdominal obesity (taking into consideration population differences), elevated level of triglycerides, reduced HDL cholesterol, hypertension and fasting hyperglycemia. Genetic predispositions and environmental factors, such as lack of physical activity and improper diet are considered to be responsible for MetS development. Therefore, prevention and treatment of MetS should be based first of all on a change in modifiable lifestyle factors, among which proper diet is of essential importance.

3

Salivary glands dysfunction and oral manifestations in diabetes and obesity - review

88%

Garbowska M., Kurek K., Żendzian-Piotrowska M., Bartłomiej Łukaszuk B.

Progress in Health Sciences

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2018

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vol. 8(1)

130-140

EN

Diabetes mellitus (DM) is a group of metabolic disorders of multiple etiologies characterized by hyperglycemia. In 2014 it affected approximately 422 million individuals worldwide. Unfortunately, it is associated with a set of co-morbidities that contribute to a significantly reduced, i.e. 5-10 years, life expectancy. The following review will discuss the most common long-term complications of diabetes. For practical reasons we decided to narrow our interests to its very widespread, even 90-95% of the cases, form - type 2 diabetes mellitus. During the discussion particular emphasis will be placed on the salivary glands function since previous investigation has confirmed its relation to many burdensome oral diseases, while the effective medical care over diabetic patients requires better understanding of pathomechanisms of its (i.e. diabetic) oral manifestations.

4

The significance of glycocalyx in medicine

88%

Wawrzkowicz J., Witek M., Winiarczyk I., Wyleciał M., Drożdżyk A., Szelengiewicz K.

European Journal of Clinical and Experimental Medicine

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2021

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issue 3

246-250

EN

Introduction. The glycocalyx is a gel-like layer covering the membrane of many cells, especially cells of epithelial tissue. It consists of membrane-bound proteoglycans, glycosaminoglycan chains, glycoproteins, and adjacent proteins. Glycocalyx is necessary in maintaining the permeability of vessels, modulation of inflammatory responses and interactions between cells. It is also involved in cell adherence, mobility, mechanotransduction, regulation of the cell cycle and cell. Abnormalities in the structure and function of the glycocalyx underlie many diseases and disorders such as dry eyes disease, diabetes and its complications as well as sepsis. Aim. In this review, we present the current view on the role of glycocalyx in human diseases. Material and methods. This review was performed according to latest literature from the following databases: EBSCO, PubMed, Science Direct, and Springer Link. Analysis of the literature. Pathological mechanisms such as disruption of the glycocalyx barrier and decreased hydration of the ocular epithelial surface cause dry eye disease. During hyperglycaemia, glycocalyx dysfunction occurs, which leads to its dysfunction and activation of the prothrombotic system. Moreover, the increase in the concentration of hyaluronidase leads to increase in the plasma hyaluronan levels and promotion of endothelial dysfunction. Additionally, degradation of glycocalyx in sepsis prevails over increased synthesis of its components strongly favors its enhanced enzymatic degradation. Conclusion. A better understanding of glycocalyx impairment in disease could alter therapeutic strategies to improve patient outcomes.

5

Relationship between type 2 diabetes and periodontal disease

88%

Popławska-Kita A., Siewko K., Szpak P., Król B., Telejko B., Klimiuk P., Waszkiel D., Górska M., Szelachowska M.

Progress in Health Sciences

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2013

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vol. 3

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issue 2

137-144

EN

Purpose: To assess periodontal status in type 2 diabetes (T2D) to compare the findings between diabetic and non-diabetic individuals using Community Periodontal Index (CPI) and Oral Hygiene Index (OHI). Associations between glycemic control and inflammatory biomarkers were analyzed among T2D patients in comparison with controls. Materials and methods: A total of 135 patients with T2DM (F64/ M71) and 40 healthy controls (CG) (F21/M19) individuals were assessed. Periodontal status was assessed using CPI, OHI and tooth number. Blood samples were analyzed for glycemic control markers (FPG and HbA1c), inflammatory mediators (CRP, TNF-α, Il-1) and lipids (TG, TC, HDL, LDL). Study participants with T2D were classified into 2 groups according to their level of HbA1c: good metabolic control group (GMC) had HbA1c below 7.0% and poor metabolic control group (PMC) had HbA1c above 7.0%. Results: The prevalence of periodontitis in all patients with T2D was 83.5%, 82.7% in GMC group, and 86.4% in PMC group as compared to CG 57.7%. The number of sextants with CPI codes of 3 was higher in PMC T2D as compared to controls. We observed significant positive correlation between OHI and: age (R=0,566, p<0.001), creatinine concentrations (R=0.377, p<0.01), tooth number (R=0.841, p<.001), CPI3 (R=0.518, p<0.01) and CPI4 (R=0.498; p<0.001). Negative correlation (R=-0.388; p<0.01) between OHI and IL-1 concentrations and number of sextants with CPI1 was found. Conclusion: The study indicated that type 2 diabetic subjects should improve their oral hygiene practices and that the control of blood glucose levels ought to be emphasized.

6

The analysis of screening costs for hypercholesterolemia and hyperglycemia as part of obligatory examinations of employees

75%

Marcinkiewicz A., Olejniczak D., Śliż D., Staniszewska A.

International Journal of Occupational Medicine and Environmental Health

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2021

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vol. 34

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issue 5

581-589

EN

ObjectivesHigh prevalence of hyperlipidemia and hyperglycemia requires searching for efficient and cost-effective methods of an early detection of these disorders. In Poland, obligatory employee medical check-ups could be a solution.Material and MethodsThe study included a group of university employees who underwent obligatory occupational examinations in 2018. Each employee had an additional lipid (unit cost: EUR 2.56) and blood glucose profile (EUR 0.93) done. The number of respondents involved in the study was 850 (340 males and 510 females), and their average age was 47 years (SD = 11 years). The education distribution was as follows: employees with secondary vocational and general education (physical, frontline and administrative workers): 176 (age: M±SD 50.3±10.3); employees with a university degree (academics with an M.Sc. or/and Ph.D. title and administrative staff): 535 (age: M±SD 43.6±9.8); and academics with a university title (Ass. Prof. and/or Prof.): 139 (age: M±SD 56.2±10.2).ResultsDyslipidemia (elevated total cholesterol ≥190 mg/dl and/or low-density lipoprotein cholesterol ≥115 mg/dl) was reported in 560 workers (65.9%). Hyperglycemia (fasting glucose ≥100 mg/dl) was observed in 256 workers (31%). The total cost of detecting a single case of dyslipidemia and hyperglycemia was EUR 3.88 and EUR 3.09, respectively. Divided by age groups, the costs were as follows: EUR 4.34 and EUR 4.53 in the age group <45 years; EUR 3.56 and EUR 2.42 in the age group ≥45 years. The costs of detecting a single case of dyslipidemia and hyperglycemia in employees aged ≥45 with regard to education were as follows: EUR 3.20 and EUR 2.07 in persons with secondary vocational and general education; EUR 3.40 and EUR 2.80 in persons with a university degree; and EUR 4.38 and EUR 2.28 in persons with a university title.ConclusionsDue to the fact that the reporting rate for screening tests in the framework of occupational medicine is high, the cost of occupational screening tests for dyslipidemia and hyperglycemia can be lower than the cost of screening tests in the general population.

Refine search results

Effects of exposure to electromagnetic field radiation (EMFR) generated by activated mobile phones on fasting blood glucose

Prevention and nutritional therapy of metabolic syndrome

Salivary glands dysfunction and oral manifestations in diabetes and obesity - review

The significance of glycocalyx in medicine

Relationship between type 2 diabetes and periodontal disease

The analysis of screening costs for hypercholesterolemia and hyperglycemia as part of obligatory examinations of employees