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Occupational allergy to horse allergens: More than exposure to horses!

100%
Liccardi G., Calzetta L., Sapio C., Rogliani P.
International Journal of Occupational Medicine and Environmental Health
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2016
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vol. 29
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issue 5
721-723
2
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Don't we overestimate drug allergies in children?

100%
Podlecka D., Jerzyńska J., Brzozowska A.
International Journal of Occupational Medicine and Environmental Health
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2023
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vol. 36
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issue 5
632-642
EN
Objectives On average about 10% of parents report hypersensitivity to at least 1 drug in their children. After diagnosis process a few of these reactions are being confirmed as drug hypersensitivity reactions. The aim of the study was to assess the real-life prevalence of drug hypersensitivity in children based on drug provocation tests. Material and Methods The authors included 113 children, aged 4–18 years, referred to Pediatrics and Allergy Clinic in Łódź, Poland, due to incidence of adverse reaction during treatment. Medical history regarding allergies to drugs was taken in accordance to the form developed by the United States Food and Drug Administration Adverse Event Reporting System. Skin prick tests, intradermal test and drug provocation test were performed in all patients. Results In all 113 patients suspected of drug allergy, after all diagnostic procedures, the authors proved IgE-mediated allergy to β-lactams, nonsteroid anti-inflammatory drugs, local anesthetics in 19 patients (16.8%). Previous history of allergy was a risk factor for drug allergy in studied patients (p = 0.001). The most frequent symptoms of allergy were urticaria and erythematous papular rash. Conclusions Drug allergy is a difficult problem in the practice of a doctor and is difficult to diagnose, especially in the pediatric population. It seems that too often isolated symptoms reported during infection or disease are taken as a symptom of drug allergy, and not as a symptom resulting from the course of the disease.
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The incidence of lidocaine allergy in dentists: an evaluation of 100 general dental practitioners

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Janas-Naze A., Osica P.
International Journal of Occupational Medicine and Environmental Health
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2019
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vol. 32
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issue 3
333-339
EN
Objectives Local anesthetics are some of the most common drugs used in dentistry and about 6 million people daily around the world are subjected to their effect in procedures performed by a similar number of dentists who, in turn, are usually not aware of the fact of being allergic to this group of medications. Assuming that dentists are also patients, and that in their daily practice the contact with the allergen is very frequent, it is essential to assess the incidence of allergy to lidocaine in general dental practitioners. Material and Methods The authors evaluated a group of 100 general dental practitioners in whom adverse reactions similar to anaphylaxis occurred after local anesthesia. The study included individuals who, in their thorough medical history, had experienced episodes of such reactions regarding the skin, airways, gastrointestinal tract and other areas. Results The relations between type I hypersensitivity and certain symptoms, time from exposure to their appearance, as well as time from the last episode were investigated. Allergy to lidocaine was detected in 17 subjects – type I hypersensitivity was diagnosed in 13 cases (skin prick test – 7; intradermic test – 6) and 4 subjects had IgE-independent allergy (patch test). In the group where type I hypersensitivity was detected, urticaria, angioedema and rhinitis were indicated as inclusion criteria more often than among other subjects. According to the results, the occurrence of angioedema increased the risk of detection of type I hypersensitivity 68.8 times, and 1 year longer period from the last episode decreased this risk by circa 55%. Conclusions The most important, from the clinical practice point of view, was to show the relation between the medical history indicating the anaphylactic nature of the lidocaine intolerance, and an allergy confirmed by skin tests. Int J Occup Med Environ Health. 2019;32(3):333–9
4
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The effect of upper respiratory allergy on acute respiratory response to ambient air pollution during physical exercise

100%
Kocot K.
International Journal of Occupational Medicine and Environmental Health
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2020
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vol. 33
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issue 5
649-660
EN
ObjectivesAmbient air pollution is related to adverse respiratory effects. Because of a popular habit of recreational physical activity, the effects of exposure to increased levels of air pollution attract increasing attention. It remains unclear whether the allergy status has an impact on acute responses to air pollution exposure during brief exercise in young adults. The aim of the study was to determine if acute respiratory responses to ambient air pollution during physical exercise differ between young subjects with and without a history of upper respiratory allergy.Material and MethodsOverall, 41 young males with (N = 15, 36.6%) and without allergy (N = 26, 63.4%) performed short moderate-intensive cycle-ergometer sessions in winter air pollution exposure conditions. Associations were analyzed between environmental conditions and acute physiological changes in spirometry, fractioned exhaled nitric oxide (FeNO) levels, blood pressure and pulse oximetry.ResultsNo associations between air pollution concentrations and changes in forced vital capacity, forced expiratory volume in 1 s and the Tiffeneau index were found. In the subjects without allergy, the increased air pollution concentrations recorded during exercise were associated with a post-exercise increase/a smaller decrease in FeNO (SO2: Spearman’s ρ = 0.44, NOx: ρ = 0.51, and particulate matter [PM] levels – PM10: ρ = 0.51, PM2.5: ρ = 0.52). This effect was not observed in the subjects with allergy.ConclusionsUpper-respiratory allergy may be a modifying factor in human response to air pollution during exercise. Exposure to air pollution during brief moderate-intensive exercise did not have any acute negative impact on respiratory and cardiovascular function in young males. However, in the case of FeNO, subclinical post-exercise changes related to air pollution were observed in volunteers without allergy.
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„To nie choroba czy zespół” – dziecko i współczesne dyskursy o wrażliwości

84%
Rakoczy M.
Kultura Współczesna. Teoria. Interpretacje. Praktyka
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2018
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vol. 103
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issue 4
141-156
EN
The paper presents a study of the category of hypersensitivity based on Polish parenting websites and a discourse on children and child rearing. Using discourse analysis methods and findings from new childhood studies, the author explores the current aporias regarding sensitivity. She analyses social narratives entailed in them, including those concerning child education and upbringing, related to modern biopolitics and various risk discourses according to which the responsibility for the proper control and development of the child’s sensitivity lies within the parent-expert. Based on the studied material, a thesis is formed that connects the discourse on hypersensitivity with modern, also neoliberal, thinking, pointing to the post-moralistic implications of this relationship – possible outcomes of treating child development as a strictly individualistic process. The article also shows mechanisms of depriving children of subjectivity through discursive child management, in which the child is no longer a person and becomes merely a representative of certain characteristics of a specific group of population recognized as hypersensitive.
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