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Rola systemu dopaminergicznego i serotoninergicznego w procesie podejmowania decyzji

100%
Jaracz M., Borkowska A.
Psychologia-Etologia-Genetyka
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2013
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vol. 28
9-29
XX
Decision-making is a process, consisted of a numerous mechanisms, which aim at ascribing a value to actions and environmental stimuli in a manner that allows making decisions and modifying them to maximize the probability of achieving significant goals. Most studies on the role of neurotransmitters in this process concern the dopaminergic and serotoninergic systems, interaction between both being especially relevant for the eventual action selection. The aim of the present work is to present the state-of-the-art, concerning the contribution of neurotransmitters to the decision-making process with special emphasis on pharmacological and genetic studies concerning the dopaminergic and serotoninergic systems.
2
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Czynniki medyczne i psychologiczne wpływające na stan psychiczny pielęgniarek z długoletnim stażem pracy

88%
Nieznańska A., Kurczabińska-Luboń D., Luboń D.
Społeczeństwo i Edukacja. Międzynarodowe Studia Humanistyczne
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2015
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issue 1(16)
237-241
EN
The purpose of this study is to define medical and psychological factors characterizing the nurses with many years of the professional experience who are took part of bridging studies. Fifty nine nurses were participating in this survey. Main goal of this survey was to investigate association between clinical depression symptoms, level of neurotransmitters and the number of years in the nursing profession. Data analysis showed no symptoms of clinical depression. The level of neurotransmitters, serotonin, dopamine and noradrenaline was maintained in medium level in the whole group. Respondents were characterized by higher disposition to feel gratitude and average life satisfaction. There was no sig- nificant correlation between experience in the nursing profession, depression factors and the level of neurotransmitters.
3
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Optimization of ultra-performance liquid chromatography (UPLC) with fluorescence detector (FLD) method for the quantitative determination of selected neurotransmitters in rat brain

75%
Stragierowicz J., Daragó A., Brzeźnicki S., Kilanowicz A.
Medycyna Pracy
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2017
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vol. 68
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issue 5
583-591
EN
Background Glutamate (Glu) and γ-aminobutyric acid (GABA) are the main neurotransmitters in the central nervous system for excitatory and inhibitory processes, respectively. Monitoring these neurotransmitters is an essential tool in establishing pathological functions, among others in terms of occupational exposure to toxic substances. Material and Methods We present modification of the HPLC (high-performance liquid chromatography) to the UPLC (ultra-performance liquid chromatography) method for the simultaneous determination of glutamate and γ-aminobutyric acid in a single injection. The isocratic separation of these neurotransmitter derivatives was performed on Waters Acquity BEH (ethylene bridged hybrid) C18 column with particle size of 1.7 μm at 35°C using a mobile phase consisting of 0.1 M acetate buffer (pH 6.0) and methanol (60:40, v/v) at a flow rate of 0.3 ml/min. The analytes were detected with the fluorescence detector (FLD) using derivatization with o-phthaldialdehyde (OPA), resulting in excitation at 340 nm and emission at 455 nm. Results Several validation parameters including linearity (0.999), accuracy (101.1%), intra-day precision (1.52–1.84%), inter-day precision (2.47–3.12%), limit of detection (5–30 ng/ml) and quantification (100 ng/ml) were examined. The developed method was also used for the determination of these neurotransmitters in homogenates of selected rat brain structures. Conclusions The presented UPLC-FLD is characterized by shorter separation time (3.5 min), which is an adaptation of the similar HPLC methods and is an alternative for more expensive references techniques such as liquid chromatography coupled with tandem mass-spectrometry (LC-MS/MS) methods. Med Pr 2017;68(5):583–591
4
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W poszukiwaniu źródeł zła. Wybrane koncepcje przyczyn zachowań z obszaru patologii społecznej

63%
Mudrak E.
Warmińsko-Mazurski Kwartalnik Naukowy, Nauki Społeczne
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2017
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issue 3
9-31
EN
In our today’s society manifestations of social pathology have become everyday occurences. Researchers have been trying for a long time to trace their origins. The nature of evil, however, is not clearly evident, obvious and/or easily understandable. The submitted paper sums up select concepts from various fields of sciences which focus on the primary causes of behavior that challenges existing societal norms. They investigate aspects of human biology as well as psychological foundations and mechanisms of the human species. The importance of social life, hich is capable to channel instincts of anti-social behaviour, should not be neglected, either.
PL
Zjawiska z obszaru patologii społecznej stają się nieodłączną właściwością współczesnych społeczeństw. Badacze nieustannie próbują znaleźć odpowiedź na pytanie, co jest ich przyczyną. Natura zła nie jest jednak oczywista, jasna, zrozumiała. Niniejszy tekst stanowi przegląd wybranych koncepcji wywodzących się z różnych dyscyplin nauki, które odnoszą się do kwestii wyjaśniania zachowań naruszających obowiązujący system normatywny. Z jednej strony – sięgają one w sferę ludzkiej biologiczności, z drugiej – podnoszą znaczenie psychologicznego funkcjonowania Homo sapiens. Nie można jednak pomijać życia społecznego, które może skanalizować instynkty oraz popędy jego uczestników w kierunku działań antyspołecznych.
5
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Neuronaukowe implikacje w podejmowaniu decyzji

63%
Majewska-Bielecka D., Nowak-Lewandowska R.
Zeszyty Naukowe ZPSB Firma i Rynek
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2019
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issue 1(55)
173-180
PL
Badania mózgu solidnie naruszyły pierwotny wizerunek człowieka racjonalnego. Celem artykułu jest próba znalezienia odpowiedzi na pytania: Jaką rolę w procesie podejmowania decyzji odgrywają struktury neuronalne? Jaki wpływ na wybory człowieka ma wiedza, doświadczenie, nastrój, różne obszary mózgu, neuroprzekaźniki? Zgodnie z afektywną koncepcją ryzyka, emocje silnie wpływają na treść podejmowanych decyzji i nie da się dokonywać bez nich niektórych wyborów. Według teorii markerów somatycznych, podejmując decyzje, decydent nieświadomie wie, która strategia jest dla niego korzystniejsza i dąży do jej wybrania. Złożony układ powiązań między różnymi obszarami mózgu określa sposób reagowania człowieka w warunkach niepewności i ryzyka.
EN
Brain research has profoundly damaged the original image of a rational human being. The aim of the article is to try to find answers to the following questions: What role do neural structures play in the decision-making process? What impact does knowledge, experience, mood, different areas of the brain, neurotransmitters have on human choices? According to the affective concept of risk, emotions strongly influence the content of decisions taken and some choices cannot be made without them. According to the theory of somatic markers, when making decisions, the decision-maker unconsciously knows which strategy is more beneficial for him and strives to choose it. A complex system of connections between different areas of the brain determines the way a person reacts in conditions of uncertainty and risk.
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