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EN
The review provides a comprehensive summary of existing literature focusing on the most serious risk factors of non-communicable diseases and collects current knowledge on their distribution, determinants, clusters, psychological and socio-economic consequences. Especially, the life-course approach is stressed, early life consequences of the later onset of chronic diseases, the risk behavior and its social, socio-economic and psychosocial determination is reviewed. Potential of preventing these harmful consequences has a lifelong approach. The aim is to demonstrate the opportunity for future health system transformation in terms of public health prevention regarding the non-communicable diseases. It is concluded that personalized lifestyle medicine should address a patient’s health by empowering them with the information they need to regain control of their health. Preventive methods should be tailored for each patient, considering such patient’s specific genes, environment, lifestyle, early life factors and social patterns of risk factors to avoid burden of health in later age. Intervention and preventive measures should target not only to individual factors but should reflect wider social, psychosocial and socio-economic consequences. It is also crucial from the point of view of public health to consider data on exposome, which are not included in epidemiological studies as well as its impact on health in the context of non-communicable diseases. Med Pr. 2021;72(5):535–48
EN
The results of research on the social genesis of coronary artery disease (CAD) based on life-cycle approach indicate that low socioeconomic status during early phases of ontogenesis is connected with increased risk of developing CAD in adulthood. It means that genesis of social health inequalities, concerning unequal social distribution of CAD, should be considered including early-life social influences. Scientific data concerning the developmental origins of non-communicable chronic diseases, especially those well described regarding CAD, constitute a significant complement to traditional research approach to social health inequalities, focused on middle-aged populations and socioeconomic influences in adulthood, and put emphasis on the role of assessment of the cumulative psychosocial risk of somatic diseases throughout the human life-cycle. This approach is particularly useful in understanding the social processes related to etiopathogenesis of chronic diseases with long latency periods, especially atherosclerosis. Health policy actions, aimed at effective diminishing of social health inequalities, should take into account the above mentioned data and should be directed not only at standard, behavioral coronary risk factors, but also at poor families and their children, who, in the light of the current knowledge, are highly predisposed to suffer from CAD in adulthood.
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