Search results

1

Comparison of two suicide attempts with long-acting insulin – The rare way to commit suicide

100%

Agnieszka Radzka A., Krystian Ciechański K., Jędrzej Tkaczyk J., Klaudia Brożyna K., Michał Tchórz M.

European Journal of Clinical and Experimental Medicine

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2018

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issue 2

151-154

EN

Introduction. In previous years, the number of suicide attempts has increased in Europe. Intoxication with hypoglycemic drugs, including insulin is a rare a tool for attempting suicide that may lead to a severe patient status. Aim. The aim of the study was to assess the severity of insulin poisoning with examples of two patients. Methods. The analysis of clinical history of patients and review of available literature. Results. A 22-year-old patient was hospitalized in the Department of Toxicology and Cardiology due to a suicide attempt in the way of insulin poisoning; time of poisoning was unknown, and the level of glucose was indeterminable. The patient was treated with intensive specific pharmacotherapy. After hospitalization, which lasted 5 months, the patient’s condition had been stabilized but with no verbal contact and quadriplegic paralysis. Another patient was a 41-year-old woman hospitalized two times in the Department of Toxicology and Cardiology due to the insulin poisonings. In each case of hospitalization of this woman, severe recurrent hypoglycemia was observed up to 25 mg% until the fifth day of hospitalization and the treatment used improved the patient’s condition and there was no development of serious complications. Conclusion. Normally effective treatment at the right time can recover the patient completely

2

Are platinum nanoparticles safe to human health?

75%

Czubacka E., Czerczak S.

Medycyna Pracy

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2019

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vol. 70

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issue 4

487-495

EN

Platinum nanoparticles (PtNPs) have been widely used not only in industry, but above all in medicine and diagnostics. However, there are disturbing reports related to the toxic effects of nanoplatinum, which is the main reason why the authors of this study have decided to review and analyze literature data related to its toxicity and impact on human health. While PtNPs may be absorbed by the respiratory and digestive tract, and can penetrate through the epidermis, there is no evidence concerning their absorption through the skin. Platinum nanoparticles accumulate mainly in the liver and spleen although they also reach other internal organs, such as lungs, kidneys or heart. Toxicokinetics of platinum nanoparticles depends strongly on the particle size. Only few studies regarding platinum nanoparticles toxicity have been conducted. Animals intratracheally exposed to platinum nanoparticles have demonstrated an increased level of proinflammatory cytokines in bronchoalveolar lavage which confirms inflammatory response in the lungs. Oral administration of PtNPs can cause inflammatory response and induce oxidative stress. Nanoplatinum has been found to induce hepatotoxicity and nephrotoxicity via the intravenous route. It can cause DNA damage and cellular apoptosis without significant cytotoxicity. There are no research studies on its carcinogenicity. Fetal or maternal toxicity has not been observed, but an increased mortality and a decreased growth of the offspring have been demonstrated. Platinum nanoparticles may permeate the skin barrier but there is no evidence for their absorption. Due to the insufficient number of tests that have been carried out to date, it is not possible to clearly determine the occupational exposure limit value; however, caution is recommended to employees exposed to their effects. Med Pr. 2019;70(4):487–95

3

2-naphthylamine toxicity

75%

Czubacka E., Czerczak S.

Medycyna Pracy

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2020

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vol. 71

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issue 2

205-220

EN

In the past, 2-naphthylamine (2-NA) was used for the production of azo dyes, as an antioxidant in the cable industry and in the rubber industry. Despite the fact that 2-NA is not produced on an industrial scale, it is still used in small quantities as a model bladder carcinogen in laboratories, and also for sewage control, water analysis and oxytocinase assays. In addition, it is detected in the air in coke ovens, where it is formed as one of the pyrolysis products. The main aim of this work is to provide an actual literature review for health risk assessments related to 2-NA which is still used in laboratories. Occupational exposure to 2-NA is important for the respiratory tract, mucous membranes and the skin, and, to a lesser extent, for absorption from the gastrointestinal tract. It is absorbed into the body through the skin and by inhalation, and then undergoes metabolic changes. Most of the absorbed 2-NA dose is excreted in the urine, in the form of metabolites, metabolites conjugated to acids, and even in an unchanged form. Based on literature data, the effects of 2-NA toxicity in sub-chronic and chronic exposure include contact dermatitis, chronic cystitis and bladder cancer. The authors have concluded that it is recommended to determine the occupational exposure limit which will allow preparing the exposure assessment of people at work. Med Pr. 2020;71(2):205–20

4

Analiza występowania zatruć u pacjentów leczonych w oddziale toksykologii w Rzeszowie w latach 2011–2013

75%

Filip D., Kucaba G., Załucka J., Ozga D., Wojtaszek M.

Medical Review

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2015

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issue 3

244-254

PL

Wstęp. Wraz z rozwojem cywilizacji lawinowo wzrasta liczba zagrożeń i nieprzewidzianych wypadków, a wśród nich zatruć. Zarówno przypadkowe jak i celowe narażenie na substancje szkodliwe są problemem nie tylko oddziałów toksykologii, ale także pracowników systemu ratownictwa medycznego. Cel pracy. Celem pracy była analiza zatruć pod względem rodzaju i ciężkości wśród pacjentów leczonych w Klinicznym Oddziale Intensywnej Terapii i Anestezjologii z Ośrodkiem Ostrych Zatruć Szpitala Wojewódzkiego nr 2 im. św. Jadwigi Królowej w Rzeszowie w latach 2011–2013 oraz czynników mających wpływ na częstość występowania zatruć. Materiał i metodyka. Badania przeprowadzono na podstawie oddziałowych zestawień zbiorczych pacjentów leczonych z powodu zatrucia. Na podstawie udostępnionych danych wyodrębniono płeć, wiek, rodzaje ciężkości zatruć, rodzaj zatrucia, efekt terapii, tryb przyjęcia oraz wypisu. Wszystkie wykresy i tabele wykorzystane w pracy wykonano za pomocą programu statystycznego IBM SPSS Statistic. Wyniki. Liczba pacjentów leczonych z powodu zatruć w oddziale wzrastała w poszczególnych latach z 332 do 491. Częściej hospitalizowani byli mężczyźni a najczęstszą przyczyna pobytu było zatrucie alkoholem etylowym lub inne stany związane z nadużyciem tego alkoholu. Zaobserwowano wzrost liczby ciężkich zatruć w poszczególnych latach z 5,12% w 2011 do 11% w 2013. Zaobserwowano również wzrost liczby pacjentów kierowanych z niniejszego oddziału do dalszego leczenia w innym szpitalu. Wnioski. Stwierdzono sukcesywny wzrost liczby hospitalizowanych pacjentów oraz ciężkości zatruć. Częściej zatruciom ulegali mężczyźni, a najczęstszą przyczyną zatrucia jest alkohol etylowy. Bardzo mały odsetek zatruć zakończył się zgonem. Ponad połowa zatrutych leczyła się na choroby współistniejące. Do SOR i do oddziału toksykologii pacjenci najczęściej przywożeni byli przez zespoły ratownictwa medycznego.

EN

Introduction. The number of accidents and emergencies, among them poisonings, is currently increasing rapidly. Both accidental and intentional exposure to toxic substances is not only the problem of toxicology departments but also emergency medical system. Aim of study. The aim of the study was to analyze poisonings in terms of a type and severity among the patients treated at the Department of Toxicology of St. Hedvig Provincial Hospital No.2 in Rzeszów in 2011-2013 and factors affcting the incidence of poisonings. Material and methods. The study analyzed cumulative statistics from a hospital department on intoxicated patients. Sex, age, type and severity of poisoning, effct of therapy, the way of admission and discharge were collected from the available data. All graphs and tables in the paper were elaborated by means of IBM SPSS Statistic software. Results. The number of patients treated for poisoning in the branch increased during researched period from 332 to 491. Men were hospitalized more often than women and the most common cause of the stay was ethanol poisoning or other conditions associated with alcohol abuse. The increase in the number of severe poisonings in the subsequent years from 5.12% in 2011 to 11% in 2013 was observed. The increase in the number of patients referred for further treatment to another hospital was also noted. Conclusions.The increase in the number of hospitalized patients and the severity of poisonings was found. The men were more often prone to poisonings and the most common reason of poisoning was ethyl alcohol. A very small percentage of the poisonings was fatal. More than a half of intoxicated patients had comorbidities. Most frequently patients were transported to the emergency department and the department of toxicology by emergency medical service.

5

Self-poisonings before and during the initial year of the COVID-19 pandemic in northern Poland

75%

Sein Anand Ł., Sein Anand J.

International Journal of Occupational Medicine and Environmental Health

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2022

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vol. 35

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issue 5

527-535

EN

Objectives The objectives of this study included evaluating and reporting on the initial impact of the COVID-19 pandemic and preventive measures in the form of a lockdown on self-poisoning tendencies in northern Poland. Material and Methods The authors retrospectively analyzed medical records of all patients (N = 2990) admitted to the Pomeranian Center of Toxicology in 2018–2020. Of those, further analysis included 2140 patients who had been admitted because of a suicide attempt by self-poisoning. The authors also selected a group of 40 patients on the basis of a self-reported direct relationship of the suicide attempt with the COVID-19 pandemic or the imposed lockdown. Results The rates of suicide attempts in toxicological patients over the years ranged 68.18–75.3%. The patients were predominantly female, with age between M±SD 33.2±16.9 and 36.0±16.4. Each year, over 60% of patients were admitted during their first attempt and were treated psychiatrically prior to their attempt, with differences observed in the COVID-19-related group. The alcohol intoxication during the suicide attempt was confirmed in 37.40–43.53% of the patients, with a higher rate of 52.50% observed in the COVID-19-related group. The main self-reported reason for the suicide was a romantic relationship conflict or breakup, and a conflict and/or violence in the family. The most frequent agents were over-the-counter painkillers, antidepressants, antipsychotics and benzodiazepines or Z-drugs. Conclusions During the initial year of the COVID-19 pandemic, there was a fall of suicide attempts by self-poisonings in northern Poland, significant only in the case of women. The self-reported reasons were similar in all years, with mainly minor changes. There was also an increase in attempts made using benzodiazepines or Z-drugs seen in 2020 and in the COVID-19-related group. The authors believe that there is a need for multi-center, large-scale prospective studies that would provide better insight into the pandemic-related suicidal trends.

6

Cardiogenic shock induced by a high dose of intravenous morphine

75%

Sein Anand Ł., Korolkiewicz P. K., Sein Anand J.

International Journal of Occupational Medicine and Environmental Health

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2021

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vol. 34

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issue 1

133-138

EN

Morphine is an opiate alkaloid characterized by various clinical effects, among which the most prominent are its analgesic and psychoactive effects. It also has a prominent depressive effect on the respiratory and cardiovascular system. Because of its psychoactive effect, morphine is very addictive and often used as a recreational narcotic. As a medication, it has found its use as an analgesic agent in chronic pain treatment, in hemorrhagic shock, and in acute heart failure with pulmonary edema. Albeit, morphine use in heart failure is controversial, based on many observational studies showing the negative effect on the outcomes of the patients treated with morphine during acute cardiovascular incidents. In this report, the authors present a case of cardiogenic shock (CS) with transient left ventricular ejection fraction reduction, occurring in a patient attempting suicide using a high dose of intravenous morphine sulphate administration. Other CS causes were ruled out. To the best of the authors’ knowledge, this is the second case of a morphine-related CS reported in literature.

7

Acute intentional poisonings within an urban agglomeration in Poland in 2004–2013

75%

Piekarska-Wijatkowska A., Kobza-Sindlewska K., Przyłuska J., Krakowiak A.

International Journal of Occupational Medicine and Environmental Health

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2019

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vol. 33

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issue 1

77-90

EN

ObjectivesThe aim of the research was to analyze the nature of changes and tendencies observed in the frequency, circumstances and causes of acute intentional poisonings within the agglomeration of Łódź, Poland. The study related to adults.Material and MethodsAs the research material, medical records of patients hospitalized due to an acute poisoning in the Department of Toxicology in Łódź were used. Information on the hospitalized patients was gathered in the database created in accordance with the assumed criteria and an approved system of the collection of variables describing the issues of intentional acute poisonings.ResultsIn the analyzed period, within the group of 18 918 adult patients hospitalized due to an acute poisoning, male patients prevailed, accounting for 57.17% of the whole group. Intentional poisonings constituted 40.19% of all poisonings, with women dominating within that group of patients – accounting for approximately 58.63%. The largest group was formed by young people, 18–35 years old, accounting for 43.22%. The average age of the intentionally poisoned patients showed an upward tendency; this tendency concerned women to a larger extent. Medications played the most powerful role in acute intentional poisonings. Within the whole population, they were responsible for 97.27% of intoxications. The analysis of the dynamics of changes in the percentage of patients referred for further mental treatment revealed that the number of patients continuing hospital treatment in psychiatric wards tended to grow.ConclusionsObservations indicating that women are more likely to attempt intentional poisoning, and that the number of patients with psychiatric disturbances tended to grow in the analyzed period, demonstrate an urgent need for preventive measures to be taken in the local communities.

8

The overview of current evidence on the reproductive toxicity of dibutyl phthalate

75%

Czubacka E., Czerczak S., Kupczewska-Dobecka M. M.

International Journal of Occupational Medicine and Environmental Health

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2021

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vol. 34

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issue 1

15-37

EN

Over the past years, many legitimate concerns have been raised about the effects of dibutyl phthalate (DBP) as an endocrine disruptor, especially on reproduction. The aim of this publication is to critically review the literature related to the developmental and reproductive toxicity of DBP in animals. Several electronic databases were systematically searched until 2019. Studies were qualified for the review if they: linked exposure to DPB with reproduction, were published in English after 1990, and were conducted on animals. In the studies of the testicular effects of DBP on experimental animals, the most common effects of exposure included reduced fertility, atrophic changes in male gonads, degenerative changes in the epididymis, as well as a reduction in sperm count and motility, cryptorchidism, hypospadias, poor sperm quality and other genital defects (decreased testicular weight, delayed spermatogenesis, Leydig cell aggregation, impaired Sertoli cell maturation, and significant inhibitions of testicular enzymes). The embryotoxic effects of DBP on laboratory animals included mainly an increase in fetal resorption and a decrease in live births. The teratogenic effects of DBP also manifest as skeletal malformations in fetuses, malformations of male gonads and other genital effects. On the basis of the literature data, it is clearly demonstrated that DBP shows anti-androgenic effects; however, there are also reports confirming its weak estrogenic effect. Additionally, lower doses cause more adverse effects than the highest dose, which is an important fact because of the widespread environmental exposure to DBP. The studies clearly confirm that DBP is an endocrine disruptor.

9

Aconite – a Poison, or a Medicine? Ancient and Early Byzantine Testimonies

75%

Jagusiak K., Tadajczyk K. T.

Studia Ceranea

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2022

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vol. 12

119-134

EN

Aconite (Aconitum napellus) was one of the most notorious, poisonous plants in the ancient world. Its dangerous, lethal power – present in leaves, roots, stem, and tuber – was well known to the Greeks and the Romans from the earliest times. Evidence of this phenomenon is not only present in archaeological findings, but also in many writings – biographies, poems, legal codes, etc. However, the most precise and detailed accounts come from treatises written by botanists, physicians and encyclopaedists, like Theophrastus, Nicander, Pliny the Elder, Dioscorides, or Galen, and by early Byzantine authors, Oribasius, Aetius of Amida, and Paul of Aegina. In their testimonies, one can find descriptions of aconite, its influence on the human body (and animals), and remedies for affected people. In contrast, there are few passages from these sources that inform the readers about the healing properties of aconite. According to these fragments, carefully administered, aconite could be helpful in some therapies, but its use was extremely hazardous, as even a small part of the plant could kill a man.

10

Zastosowanie entomotoksykologii w szacowaniu czasu i ustaleniu przyczyny zgonu

63%

Stojak J.

Problemy Kryminalistyki

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2017

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issue 295

18-25

PL

Entomotoksykologia pozwala na oszacowanie czasu i przyczyny zgonu w przypadkach, gdy zwłoki uległy rozkładowi i tkanki niezbędne do analiz toksykologicznych nie są już dostępne. Uzyskanie informacji o potencjalnie obecnych w ciele denata substancjach toksycznych jest możliwe poprzez ich izolację z obecnych na zwłokach lub w ich pobliżu larw i poczwarek przedstawicieli muchówek (Diptera) i/lub osobników dorosłych, np. chrząszczy (Coleoptera). Celem artykułu jest podsumowanie dotychczasowego stanu wiedzy z zakresu entomotoksykologii z wykorzystaniem przykładów z literatury oraz zaprezentowanie wpływu wybranych substancji toksycznych i leków na rozwój żerujących na zwłokach larw owadów.

EN

Entomotoxicology allows the estimation of the post-mortem interval and the determination of the cause of death in cases in which the corpse has decomposed and the tissues necessary for toxicological analysis are no longer available. Obtaining information about toxic substances potentially present in the body is possible by isolation of larvae and pupae of true flies (Diptera) and/or adult forms of, e.g., beetles (Coleoptera) present on or near the corpse. This article was intended to summarize the current knowledge in the field of entomotoxicology, including examples from the literature, and to present the impact of selected toxic substances and medicines on the development of necrophagous larvae of insects.

11

Zanieczyszczenia wód powierzchniowych metalami ciężkimi i związkami organicznymi: farmaceutykami, narkotykami i pestycydami

51%

Szymonik A.

Edukacja Biologiczna i Środowiskowa

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2014

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issue 2

34-40

PL

Badania prowadzone w ostatnich latach potwierdziły, że wody powierzchniowe całego świata, w tym Polski, są zanieczyszczone związkami organicznymi i metalami ciężkimi. Związki organiczne, to m.in. farmaceutyki (diklofenak, naproksen, ibuprofen, estrogeny, antybiotyki), pestycydy czy narkotyki (kokaina, amfetamina i jej pochodne), a najczęściej identyfikowane metale w wodach powierzchniowych to: Ni, Hg, As, Pb, Cd. Związki te mogą rozpuszczać się w wodach powierzchniowych i kumulować w osadach rzecznych. Co więcej, farmaceutyki zidentyfikowano w wodach przeznaczonych do spożycia. Wszystkie wymienione związki stanowią duże wyzywanie dla ochrony środowiska i ekologii, gdyż ich obecność w wodach powierzchniowych jest wynikiem mało skutecznych procesów oczyszczania ścieków. Problem występowania farmaceutyków, metali ciężkich, pestycydów a w ciągu ostatnich 10 lat nielegalnych substancji odurzających dotyczy wód powierzchniowych na całym świecie. Obecność metali ciężkich, w tym Ni, Cd potwierdzono w rzece Rhine w Niemczech i w osadach rzecznych rzeki Kłodnicy w Polsce. Pb oznaczono w rzekach na terenie Czech. Metale ciężkie (Ni, Cd, Pb) zidentyfikowano w osadach rzecznych na terenie Polski (rzeki Wisła, Kłodnica, Przemsza). Farmaceutyki zidentyfikowano w rzekach na terenie Polski: w Warcie, Odrze, Wiśle, Wierzycy i Kanale Gliwickim. Oznaczone leki należały do grupy niesteroidowych leków przeciwzapalnych oraz żeńskich hormonów płciowych. W rzekach na terenie Hiszpanii zidentyfikowano substancje lecznicze należące do kilku grup terapeutycznych. Farmaceutyki oznaczono w wodach przeznaczonych do spożycia. W rzekach na terenie Czech i Turcji zidentyfikowano obecność groźnych dla zdrowia ludzkiego pestycydów: DDT, HCH, HBC. W ciągu ostatnich lat pojawiły się doniesienia o obecności w wodach powierzchniowych narkotyków, w niewielkim stężeniu, poniżej 10 ng/l.

EN

Studies in the recent years have confirmed that surface water around the world, including Poland, are contaminated with organic compounds and heavy metals. Organic compounds include pharmaceuticals (diclofenac, naproxen, ibuprofen, estrogens, antibiotics), pesticides or drugs (cocaine, amphetamine and its derivatives). The most common metals identified in surface waters were: Ni, Hg, As, Pb, Cd. These compounds can accumulate in surface waters, in river sediments. Pharmaceuticals have been identified in waters intended for human consumption. All of these compounds are large calling for the protection of the environment and ecology. Their presence in surface waters is the result of ineffective wastewater treatment processes. The problem of the occurrence of pharmaceuticals, heavy metals, pesticides, and over the past 10 years of illegal drugs applies to surface waters throughout the world. The presence of heavy metals, Ni, Cd was confirmed in the Rhine river in Germany and river sediments of the river Kłodnica in Poland. Pb was determined in rivers in the Czech Republic. Heavy metals (Ni, Cd, Pb) have been identified in river sediments in Polish (river Vistula, Kłodnica, Przemsza). Pharmaceuticals have been identified in Polish rivers: Warta, Odra, Vistula, Wierzyca and Kanał Gliwice. Identified pharmaceuticals belong to the group of non-steroidal anti-inflammatory drugs and female sex hormones. In Spanish rivers, there were identified pharmaceuticals belong to several therapeutic groups. Pharmaceuticals were determined in waters intended for human consumption. In Czech Republic and Turkey, researchers identified the presence of dangerous to human health pesticides: DDT, HCH, and HBC. In recent years, there have been reports of the presence of drugs in surface waters, at low concentrations, less than 10 ng/l.

12

Nowe zagrożenie zawodowe i środowiskowe – nanoplastik

51%

Rakowski M., Grzelak A.

Medycyna Pracy

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2020

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vol. 71

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issue 6

743-756

EN

Problems arising from the accumulation of plastic waste in the environment have become global. Appeals to stop the usage of disposable drinking straws or plastic cutlery did not come out without reason – 320 million tons of plastic products are produced annually, of which 40% are disposable items. More and more countries and private enterprises are giving up these types of items in favor of their biodegradable substitutes, e.g., cardboard drinking straws. Plastic waste in the environment is subject to a number of physicochemical interactions and biodegradation in which bacteria are involved. By using synthetic waste, they reduce the size of plastic garbage while increasing its dispersion in the environment. Small plastic particles, invisible to the naked eye, are called nanoplastic. Nanoplastic is not inert to living organisms. Due to its size, it is taken up with food by animals and passed on in the trophic chain. The ability to penetrate the body’s barriers through nanoplastic leads to the induction of biological effects with various outcomes. Research studies on the interaction of nanoplastic with living organisms are carried out in many laboratories; however, their number is still a drop in the ocean of the data needed to draw clear-cut conclusions about the impact of nanoplastic on living organisms. There is also no data on the direct exposure to nanoplastic contamination at workplaces, schools and public utilities, standards describing the acceptable concentration of nanoplastic in food products and drinking water, and in vitro tests on nanoparticles other than polystyrene nanoparticles. Complementing the existing data will allow assessing the risks arising from the exposure of organisms to nanoplastic. Med Pr. 2020;71(6):743–56

PL

Problemy wynikające z gromadzenia się w środowisku plastikowych odpadów stały się globalne. Apele o zaprzestanie wykorzystywania jednorazowych słomek do napojów czy plastikowych sztućców nie pojawiły się bez powodu – rocznie produkuje się 320 mln ton wyrobów plastikowych, z których 40% to przedmioty jednorazowego użytku. Coraz więcej państw i prywatnych przedsiębiorstw rezygnuje z przedmiotów plastikowych na rzecz ich biodegradowalnych zamienników, np. tekturowych słomek do napojów. W środowisku plastikowe odpady podlegają wielu oddziaływaniom fizykochemicznym oraz biodegradacji, w której biorą udział bakterie. Bytując na odpadach syntetycznych, powodują zmniejszenie ich rozmiarów i zwiększają ich dyspersję w środowisku. Małe, niewidoczne gołym okiem cząstki plastiku noszą nazwę nanoplastiku. Nanoplastik nie jest obojętny dla organizmów żywych. Z uwagi na swoje rozmiary jest pobierany wraz z pokarmem przez zwierzęta i przekazywany w łańcuchu troficznym. Zdolność nanoplastiku do przenikania barier organizmu indukuje efekty biologiczne o rozmaitych skutkach. Wiele ośrodków prowadzi badania na temat nanoplastiku, jednak ich wyniki wciąż stanowią ułamek danych potrzebnych do jednoznacznego wnioskowania o jego wpływie na organizmy żywe. Brakuje także danych dotyczących bezpośredniego narażenia na zanieczyszczenie nanoplastikiem w miejscach pracy, szkołach i miejscach użyteczności publicznej, norm opisujących dopuszczalne stężenie nanoplastiku w produktach spożywczych i wodzie pitnej oraz badań in vitro na nanocząstkach innych niż polistyrenu. Uzupełnienie dostępnych danych pozwoli obiektywnie ocenić zagrożenia płynące ze strony ekspozycji organizmów na nanoplastik. Med. Pr. 2020;71(6):743–756

Refine search results

Comparison of two suicide attempts with long-acting insulin – The rare way to commit suicide

Are platinum nanoparticles safe to human health?

2-naphthylamine toxicity

Analiza występowania zatruć u pacjentów leczonych w oddziale toksykologii w Rzeszowie w latach 2011–2013

Self-poisonings before and during the initial year of the COVID-19 pandemic in northern Poland

Cardiogenic shock induced by a high dose of intravenous morphine

Acute intentional poisonings within an urban agglomeration in Poland in 2004–2013

The overview of current evidence on the reproductive toxicity of dibutyl phthalate

Aconite – a Poison, or a Medicine? Ancient and Early Byzantine Testimonies

Zastosowanie entomotoksykologii w szacowaniu czasu i ustaleniu przyczyny zgonu

Zanieczyszczenia wód powierzchniowych metalami ciężkimi i związkami organicznymi: farmaceutykami, narkotykami i pestycydami

Nowe zagrożenie zawodowe i środowiskowe – nanoplastik