Search results

1

Serum levels of vitamin D and tumour necrosis factor-alpha in adults with metabolic syndrome

100%

Rahamon S. K., Arinola O. G., Charles-Davies M. A., Akinlade K. S., Olaniyi J. A., Fasanmade A. A., Oyewole O. E., Owolabi M. O., Adebusuyi J. R., Hassan O. O., Ajobo M. B., Adigun K., Ebesunun M. O., Popoola O. O., Omiyale W., Agbedana E. O.

European Journal of Clinical and Experimental Medicine

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2021

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issue 4

306-312

EN

Introduction. Reports continue to show that a significant association exists between serum vitamin D level and metabolic syndrome (MS)-associated inflammation. However, information on the serum levels of vitamin D and alterations in inflammation in different vitamin D status is presently lacking. Aim. To determine the serum levels of vitamin D and TNF-α, and assess their possible relationship with gender in individuals with MS. Material and methods. Sixty adults with MS and 40 controls were enrolled into this case-control study. Serum vitamin D and TNF-α levels were measured and participants stratified into different vitamin D status. Results. None of the participants had vitamin D deficiency and the mean vitamin D level was similar in MS compared with the controls. However, TNF-α level was significantly higher in MS compared with the controls. Serum vitamin D level had significant inverse correlation with serum TNF-α level in MS. Also vitamin D level was significantly lower while TNF-α level was significantly higher in female-MS compared with the male-MS. Conclusion. Adults with MS have elevated TNF-α level which appears to be associated with the serum level of vitamin D. Also, females with MS have low vitamin D level and this may exacerbate the MS-associated inflammation in them.

2

Thyroid functioning, adipocytokines, bone turnover and vitamin D - review of literature

100%

Koszowska A., Brończyk-Puzoń A., Dittfeld A., Nowak J., Kulik-Kupka K., Zubelewicz-Szkodzińska B.

Progress in Health Sciences

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2016

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vol. 6(1)

188-196

EN

The most common public health problems include, among others, overweight, obesity, and cardiovascular diseases. In addition, the number of people with thyroid disturbances is still growing. Thyroid abnormalities can lead to many metabolic dysfunctions, including secondary osteoporosis, alterations in body mass, lipid profile, and insulin resistance. Recently, the studies have been focused on the connections between thyroid gland function, obesity, metabolic syndrome and cardiovascular diseases, as well as bone turnover. Fatty tissue plays an important role in whole body homeostasis. Adipose tissue hormones, such as leptin, resistin and adiponectin are proteins having immunomodulatory lproperties, and their balance is needed to control immune response, as well as inflammation processes. The following article constitutes a review of literature concerning thyroid function with regard to adipocytokines and vitamin D, as well as the influence of this gland on the skeletal system. For this purpose, Medline Pub Med base and Google Scholar were used. All the citied studies in this review article underline how much should be done to achieve more efficient treatment of thyroid disorders, specifically, how to prevent its complications, for instance, osteoporosis, over-weight, obesity or cardiovascular diseases.

3

Nutritional status of frail elderly

88%

Jaroch A., Kędziora-Kornatowska K.

Progress in Health Sciences

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2014

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vol. 4

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issue 2

144-149

EN

Introduction: Growing population of elderly requires effective medical diagnostics and help. Criteria developed by Fried et al. are most often used for the diagnosis of the frailty syndrome. An inherent element of frailty syndrome is malnu-trition. Malnutrition results from inadequate food supply, coexistence of acute and chronic diseases. Effective nutritional interventions conducted on frail older persons can prevent them from developing the frailty syndrome. Review: The prevalence of frailty in elders is 17% moreover 42.3% are prefrail. There are many scales designed to identify frailty syndrome, but the most common is the classification of Fried et al. Malnutrition is a common state in frail elderly. Basic questionnaire, which is used to diagnose malnutrition, is MNA (Mini-Nutritional Assessment). Mini-Nutritional Assessment Short-Form (MNA-SF) and Malnutrition Universal Screening Tool (MUST) also can be used. Sarcopenia, which is defined as reduced muscle mass and strength and impaired muscle performance, significantly contribute to the development of frailty. Many studies have shown that an effective method in the preventing of sarcopenia is protein supplementation. Other beneficial lifestyle and diet changes, which can help prevent the development of frailty syndrome, are adherence to the Mediterranean diet, appro-priate intake of carotenoids, vitamin E, selenium and zinc. Another important protective factor is vitamin D levels. Low serum 25(OH)D is strongly associated with frailty. Conclusions: From a nutritional point of view adherence to a Mediterranean-style diet, sufficient intake of protein, micronutrients and vitamin D, as well as regular moderate physical activity, can be crucial in the preventing of the frailty syndrome.

4

Determinants of vitamin D status among Jordanian employees: Focus on the night shift effect

75%

Alefishat E., Abu Farha R.

International Journal of Occupational Medicine and Environmental Health

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2016

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vol. 29

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issue 5

859-870

EN

Objectives To assess the association between night work and 25-hydroxy vitamin D (25OHD) levels, and to evaluate effect of potential risk factors on 25OHD levels. Material and Methods A total of 140 adult Jordanian employees were recruited. Demographic, lifestyle and working patterns data were documented through a well-structured questionnaire. Vitamin D status was assessed by measuring circulating concentrations of 25OHD. Results Mean 25OHD level was 23.8 ng/ml. No significant difference was found in 25OHD levels between the summer and winter (p = 0.46), or between males and females (p = 0.35). The female night workers had significantly lower serum 25OHD levels compared to the female day workers (p = 0.01). No significant difference in serum 25OHD levels was found between the night and day male workers (p = 0.25). The number of night shifts/month was negatively correlated with 25OHD levels in both the males and females (p = 0.01 and p = 0.007, respectively). Age was positively correlated with 25OHD levels in both the males and females (p = 0.02 and p = 0.001, respectively). Body mass index was negatively associated with 25OHD levels in the whole sample (p = 0.03), but not within each gender group (p = 0.21 for the males and p = 0.09 for the females). Smoking had no significant association with 25OHD levels (p = 0.99 for the males and p = 0.22 for the females). Conclusions Our results suggest that women working night shifts are at higher risk of 25OHD deficiency, and, consequently, of other health problems linked to 25OHD deficiency. Int J Occup Med Environ Health 2016;29(5):859–870

5

Attitude of pediatricians and family physicians regarding vitamin D supplementation for the pediatric population: when, how much, and at what dose?

75%

Kara Elitok G., Bulbul L., Bulbul A., Uslu S., Zubarioglu U., Kıray Bas E., Besnili Acar D.

Family Medicine & Primary Care Review

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2018

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issue 4

332-336

6

Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland

75%

Baczyńska-Strzecha M., Kalinka J.

International Journal of Occupational Medicine and Environmental Health

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2017

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vol. 30

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issue 6

933-941

EN

Objectives Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. Results Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094). Conclusions Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933–941

7

Promieniowanie słoneczne a witamina D i nowotwory skóry

63%

Nowicka G.

Studia Ecologiae et Bioethicae

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2008

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vol. 6

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issue 1

6-14

EN

Solar radiation is a part of the environment of man. Ultraviolet В radiation in required for the biosynthesis of vitamin D, which is generally associated with calcium metabolism and significantly influences a wide range of metabolic systems, therefore, has a strong influence on human health. However, exposure to sunlight carries potential risks to human health. Ultraviolet radiation is a known carcinogen and excessive sunlight exposure significantly increases risk of skin cancer.

8

Procesy wpływające na zawartość witaminy D w grzybach

51%

Kobus-Cisowska J., Zawadzka A.

Zagadnienia Doradztwa Rolniczego

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2020

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issue 4 (102)

69-79

PL

Powszechnie spożywane gatunki grzybów pod wpływem działania promieni UV (światło słoneczne lub lampa UV) mogą generować istotne z punktu widzenia żywieniowego zawartości witaminy D. Główną formą witaminy D, która występuje w grzybach jest D2 (ergokalcyferol C28H44O) oraz mniejsze ilości D3 (cholekalcyferolC27H44O) i D4 (22-dihydroergokacyferol C28H46O). Witamina D3 w największych ilościach znajduje się w produktach pochodzenia zwierzęcego. Źródłem witaminy D2 są grzyby. Pomimo tego, że procesy technologiczne lub przechowywanie powodują spadek jej zawartości, zawartość D2 w grzybach może stanowić dobre jej źródło w diecie. Celem pracy była analiza aktualnych danych literaturowych w zakresie wpływu promieniowania UV na syntezę witaminy D2 w grzybach, a także wpływu ich przechowywania i obróbki termicznej na jej zawartość i biodostępność.

EN

Commonly consumed mushroom species exposed to UV radiation (sunlight or UV lamp) can generate nutritionally important amounts of vitamin D. The most common form of vitamin D in mushrooms is D2, with lesser amounts of vitamin D3 and D4, while vitamin D3 is the most common form of vitamin in animal products. Although the level of vitamin D2 in mushrooms exposed to UV radiation may decrease with storage and cooking, if they are consumed before the expiry date, the level of vitamin D2 is likely to remain above 10 μg / 100 fresh masstherefor mushrooms have the potential to be the only non-animal and unenriched food source that can provide a significant amount of vitamin D2. This review analyses current information on the role of UV radiation in enhancing concentration of vitamin D2 in mushromms, the effects of storage and cooking on D2 content, and bioavailability of vitamin D2 from mushrooms.

9

Ocena stężenia 25(OH)D u osób z zespołem metabolicznym pracujących w rolnictwie

51%

Godala M., Gaszyńska E., Moczulski D., Materek-Kuśmierkiewicz I., Krzyżak M.

Medycyna Pracy

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2021

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vol. 72

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issue 1

9-18

EN

Background: Polish data on vitamin D deficiency in the population are incomplete. Vitamin D deficiency seems to be common, but there is a lack of studies concerning the concentration of 25(OH)D in people with high UV exposure. The aim of this study was to evaluate the plasma concentration of 25(OH)D in people with and without metabolic syndrome (MS), working in agriculture, the prevalence of its deficiency in these workers, and the correlation between the plasma concentration of 25(OH)D and traditional biomarkers of cardiovascular diseases. Material and Methods: The study included 332 people working in agriculture in the Łódź voivodeship, including 231 people with MS and 101 healthy ones. The plasma concentration of 25(OH)D was assessed using the chemiluminescent immunoassay technology. The vitamin D intake was assessed using a 24-h recall questionnaire using Diet 5.0 software. Results: The mean plasma concentration of 25(OH)D was 13.64±8.01 ng/ml in MS workers, and it was significantly lower than in the healthy ones (26.61±10.12 ng/ml, p < 0.00001); the highest concentration of 25(OH)D was noted in summer months. Deficient plasma concentrations of 25(OH)D were found significantly more often in MS workers than in the controls (81.82% and 20.79%, respectively, p < 0.00001). No correlation was found between the plasma vitamin D concentration and its dietary intake. The plasma concentration of 25(OH)D correlated with age of the examined workers (r = –0.28, p = 0.023), high density lipoprotein concentration (r = 0.19, p = 0.036) and glucose concentration (Rho = –0.24, p = 0.02). A multivariate analysis of variance demonstrated that the body mass index affected significantly the mean value of the 25(OH)D concentration in MS workers. Conclusions: The concentration of vitamin D in the plasma of workers with MS was significantly lower than in the healthy controls despite the same high UV exposure; these workers also manifested significantly higher 25(OH)D deficiency than the control subjects. This study indicates the need for further research on the concentration of 25(OH)D in people with metabolic disorders regardless of UV exposure and vitamin D intake with a diet.

PL

Wstęp: Dane dotyczące stanu odżywienia witaminą D populacji polskiej są niepełne. Niedobory witaminy D wydają się powszechne, jednak nie odnaleziono polskich badań, które weryfikowałyby stężenie 25-hydroksywitaminy D [25(OH)D] u osób intensywnie eksponowanych na promieniowanie ultrafioletowe (UV). Celem pracy była ocena stężenia 25(OH)D w osoczu osób z zespołem metabolicznym (ZM) pracujących w rolnictwie, częstość jej niedoborów u tych osób oraz zależność między stężeniem 25(OH)D w osoczu a tradycyjnymi biomarkerami chorób sercowo-naczyniowych. Materiał i metody: W badaniu wzięło udział 332 mieszkańców województwa łódzkiego pracujących w rolnictwie, w tym 231 osób z ZM i 101 zdrowych. Stężenie 25(OH)D w osoczu oceniano z użyciem testu wykorzystującego technologię chemiluminescencyjnych testów immunologicznych. Spożycie witaminy D z dietą oceniano za pomocą programu Dieta 5.0 na podstawie 24-godzinnych wywiadów żywieniowych. Wyniki: Średnie stężenie 25(OH)D w osoczu pracowników z ZM wynosiło 13,64±8,01 ng/ml i było istotnie niższe niż w grupie badanych bez ZM (26,61±10,12 ng/ml, p < 0,00001). Najwyższe średnie stężenie 25(OH)D odnotowano w miesiącach letnich. U pracowników z ZM istotnie częściej niż w grupie bez ZM stwierdzono deficytowe stężenie 25(OH)D w osoczu (odpowiednio, 81,82% i 20,79%, p < 0,00001). Stwierdzono brak korelacji między stężeniem 25(OH)D a jej spożyciem z dietą. Stężenie 25(OH)D korelowało z wiekiem (r = –0,28, p = 0,023) oraz stężeniami cholesterolu HDL (r = 0,19, p = 0,036) i glukozy (Rho = –0,24, p = 0,02) w badanej grupie rolników. Wieloczynnikowa analiza wariancji wykazała, że u pracowników z ZM czynnikiem wpływającym istotnie na średnią wartość stężenia 25(OH)D był wskaźnik masy ciała. Wnioski: Stężenie witaminy D w osoczu osób z ZM było istotnie mniejsze niż u osób zdrowych mimo jednakowej, wysokiej ekspozycji na promieniowanie UV. Ponadto u osób z ZM istotnie częściej stwierdzano deficytowe stężenie 25(OH)D niż u badanych bez ZM. Uzyskane wyniki wskazują na konieczność prowadzenia dalszych badań dotyczących stężenia 25(OH)D u osób z chorobami metabolicznymi, niezależnie od wielkości ekspozycji na promieniowanie UV i spożycia witaminy D z dietą.

Refine search results

Serum levels of vitamin D and tumour necrosis factor-alpha in adults with metabolic syndrome

Thyroid functioning, adipocytokines, bone turnover and vitamin D - review of literature

Nutritional status of frail elderly

Determinants of vitamin D status among Jordanian employees: Focus on the night shift effect

Attitude of pediatricians and family physicians regarding vitamin D supplementation for the pediatric population: when, how much, and at what dose?

Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland

Promieniowanie słoneczne a witamina D i nowotwory skóry

Procesy wpływające na zawartość witaminy D w grzybach

Ocena stężenia 25(OH)D u osób z zespołem metabolicznym pracujących w rolnictwie