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Introduction: Most of the pesticides have, by nature, some degree of toxicity because they are intended to kill certain organisms and thus create a risk of damage. The use of pesticides has raised serious concerns, mainly about the potential effects on human health and especially on respiratory system. Thousands of people (from 20,000 to 220,000) lose their life due to pesticide poisoning. Ninety nine percent of them (99%) live in developing countries. Purpose: To review the literature, to identify the harmful effects of pesticides on human health, and particularly on the respiratory system, and to define the ways of dealing with them. Materials and methods: Extensive review of the relevant literature was performed via electronic databases (Medline, Pubmed, Cihnal and Google scholar) and scientific journals (Greek and international) using the appropriate key words: pesticides, respiratory symptoms, pulmonary disease and a combination of them. Results: The effects on human health due to exposure to pesticides depend on a number of factors, including the category of pesticides involved, the amount and type of active substance, as well as their form, route of contamination, exposure time and pesticides' residual dose. Pesticides, especially those that inhibit the action of cholinesterase, lead to the onset of respiratory symptoms. A number of respiratory symptoms and diseases have been associated with occupational pesticide exposures, such as wheezing, asthma cough, phlegm, dyspnoea and influenza like syndrome are reported especially among agricultural workers. Conclusions: Pesticides are dangerous substances for the human body and especially for the respiratory system, if they are used without control. Proper use of pesticides can ensure both the quality of the environment and citizen's safety and health. New scientific data require periodic review of safety levels.
EN
Introduction: Ulcerative colitis is one of the most interesting nosological entities of gastroenterology and internal medicine. This chronic autoimmune disorder of the digestive system, along with Crohn's disease, is a type of idiopathic inflammatory bowel disease. It mainly affects people during their peak reproductive age, i.e., 15 to 30 years old. It is characterized by diffuse mucosal inflammation of the large intestine, which is limited to the colon and shows alternating periods of exacerbations and remissions. Purpose: To review the world literature regarding the impact of the disease on fertility, the course of pregnancy, and consecutively, the outcome of pregnancy.Materials and methods: An extensive review of the recent national and international literature in electronic databases (Pubmed, Google Scholar) and in scientific journals was accomplished through the use of appropriate keywords. Results: The majority of women will have a chance of conceiving. For about 25% of them, conception will be achieved in the course of the disease and it will progress normally, resulting in a healthy fetal outcome. Infertility only occurs among men while they are taking medicines, whereas among women it occurs after surgery for ileoanal anastomosis. During periods of flare-ups, there is a possibility of spontaneous abortion, premature labor and birth of an infant with low birth weight. The majority of pharmaceutical formulations can be used safely both before and after pregnancy without causing any birth defects.
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