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Contrast induced acute kidney injury – is it a real problem these days?

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Musiałowski P., Musiałowska D., Gościk E., Małyszko J.
Progress in Health Sciences
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2016
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vol. 6(1)
177-182
EN
Acute kidney injury (AKI) is proven risk factor associated with higher mortality and morbidity among hospitalized patients. The widespread use contrast media opens the discussion about the acute kidney injury as a result of used contrast - contrast induced nephropathy (CIN). CIN is defined as an acute, generally reversible decline in renal function that occurs 48-72 hours after intravascular injection of contrast medium. Pre-existing renal insufficiency is characterised independent risk factor for occurrence of CI-AKI, other factors,such as diabetes mellitus, hypertension, advanced age or hemodynamic instability increase the risk of AKI, but are not characterized as independent risk factors. Published new large retrospective single-center studies presented equal risk of AKI among patients receiving contrast enhanced computer tomography if compared to unenhanced computer tomography, based on serum creatinine levels. In our review we would like to present a persisting the problem of CIN after intravenous (iv) as well intra-arterial contrast media administration
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Genetic similarities of Escherichia coli isolated from hospitalized patients

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Żórawski, M.J, Dudzik D., Musiałowska D.
Progress in Health Sciences
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2017
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vol. 7(1)
145-150
EN
Introduction: Escherichia coli is a component of human physiological flora. Pathogenic E. coli strains are a significant etiologic factor for numerous infections, mainly the urinary system, digestive system, respiratory system as well as bacteraemia and post-operative infections. Purpose: To compare the genetic similarity of Escherichia coli strains, isolated from biological material collected for routine microbiological diagnostics. Materials and methods: The examination performed on the Escherichia coli strains, isolated from material collected from patients hospitalized in various clinics and delivered for routine laboratory diagnostics. The analysis was conducted using the ADRSSR method.Results: As a result of the analysis of genetic similarities of examined strains using the ADRSSR method, nine clones were distinguished, clones A and B considered being most numerous. Clone A was predominant in samples from internal diseases clinics while cloning B – from neonatological clinics. Conclusions: The results point to a significant role of monitoring of homogeneity of bacteria strains isolated in the range of the health care providers. It is directly connected with the safety of hospitalized patients as well as effectiveness and course of the treatment. The use of the ADSRRS method gives the opportunity of early detection of the moment of colonization in the monitored place
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