Search results

1

Serum levels of vitamin D and tumour necrosis factor-alpha in adults with metabolic syndrome

100%

Rahamon S. K., Arinola O. G., Charles-Davies M. A., Akinlade K. S., Olaniyi J. A., Fasanmade A. A., Oyewole O. E., Owolabi M. O., Adebusuyi J. R., Hassan O. O., Ajobo M. B., Adigun K., Ebesunun M. O., Popoola O. O., Omiyale W., Agbedana E. O.

European Journal of Clinical and Experimental Medicine

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2021

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issue 4

306-312

EN

Introduction. Reports continue to show that a significant association exists between serum vitamin D level and metabolic syndrome (MS)-associated inflammation. However, information on the serum levels of vitamin D and alterations in inflammation in different vitamin D status is presently lacking. Aim. To determine the serum levels of vitamin D and TNF-α, and assess their possible relationship with gender in individuals with MS. Material and methods. Sixty adults with MS and 40 controls were enrolled into this case-control study. Serum vitamin D and TNF-α levels were measured and participants stratified into different vitamin D status. Results. None of the participants had vitamin D deficiency and the mean vitamin D level was similar in MS compared with the controls. However, TNF-α level was significantly higher in MS compared with the controls. Serum vitamin D level had significant inverse correlation with serum TNF-α level in MS. Also vitamin D level was significantly lower while TNF-α level was significantly higher in female-MS compared with the male-MS. Conclusion. Adults with MS have elevated TNF-α level which appears to be associated with the serum level of vitamin D. Also, females with MS have low vitamin D level and this may exacerbate the MS-associated inflammation in them.

2

Thyroid functioning, adipocytokines, bone turnover and vitamin D - review of literature

100%

Koszowska A., Brończyk-Puzoń A., Dittfeld A., Nowak J., Kulik-Kupka K., Zubelewicz-Szkodzińska B.

Progress in Health Sciences

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2015

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vol. 6

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issue 1

188-196

EN

The most common public health problems include, among others, overweight, obesity, and cardiovascular diseases. In addition, the number of people with thyroid disturbances is still growing. Thyroid abnormalities can lead to many metabolic dysfunctions, including secondary osteoporosis, alterations in body mass, lipid profile, and insulin resistance. Recently, the studies have been focused on the connections between thyroid gland function, obesity, metabolic syndrome and cardiovascular diseases, as well as bone turnover. Fatty tissue plays an important role in whole body homeostasis. Adipose tissue hormones, such as leptin, resistin and adiponectin are proteins having immunomodulatory lproperties, and their balance is needed to control immune response, as well as inflammation processes. The following article constitutes a review of literature concerning thyroid function with regard to adipocytokines and vitamin D, as well as the influence of this gland on the skeletal system. For this purpose, Medline Pub Med base and Google Scholar were used. All the citied studies in this review article underline how much should be done to achieve more efficient treatment of thyroid disorders, specifically, how to prevent its complications, for instance, osteoporosis, over-weight, obesity or cardiovascular diseases.

3

Nutritional status of frail elderly

88%

Jaroch A., Kędziora-Kornatowska K.

Progress in Health Sciences

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2014

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vol. 4

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issue 2

144-149

EN

Introduction: Growing population of elderly requires effective medical diagnostics and help. Criteria developed by Fried et al. are most often used for the diagnosis of the frailty syndrome. An inherent element of frailty syndrome is malnu-trition. Malnutrition results from inadequate food supply, coexistence of acute and chronic diseases. Effective nutritional interventions conducted on frail older persons can prevent them from developing the frailty syndrome. Review: The prevalence of frailty in elders is 17% moreover 42.3% are prefrail. There are many scales designed to identify frailty syndrome, but the most common is the classification of Fried et al. Malnutrition is a common state in frail elderly. Basic questionnaire, which is used to diagnose malnutrition, is MNA (Mini-Nutritional Assessment). Mini-Nutritional Assessment Short-Form (MNA-SF) and Malnutrition Universal Screening Tool (MUST) also can be used. Sarcopenia, which is defined as reduced muscle mass and strength and impaired muscle performance, significantly contribute to the development of frailty. Many studies have shown that an effective method in the preventing of sarcopenia is protein supplementation. Other beneficial lifestyle and diet changes, which can help prevent the development of frailty syndrome, are adherence to the Mediterranean diet, appro-priate intake of carotenoids, vitamin E, selenium and zinc. Another important protective factor is vitamin D levels. Low serum 25(OH)D is strongly associated with frailty. Conclusions: From a nutritional point of view adherence to a Mediterranean-style diet, sufficient intake of protein, micronutrients and vitamin D, as well as regular moderate physical activity, can be crucial in the preventing of the frailty syndrome.

4

Determinants of vitamin D status among Jordanian employees: Focus on the night shift effect

75%

Alefishat E., Abu Farha R.

International Journal of Occupational Medicine and Environmental Health

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2016

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vol. 29

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issue 5

859-870

EN

Objectives To assess the association between night work and 25-hydroxy vitamin D (25OHD) levels, and to evaluate effect of potential risk factors on 25OHD levels. Material and Methods A total of 140 adult Jordanian employees were recruited. Demographic, lifestyle and working patterns data were documented through a well-structured questionnaire. Vitamin D status was assessed by measuring circulating concentrations of 25OHD. Results Mean 25OHD level was 23.8 ng/ml. No significant difference was found in 25OHD levels between the summer and winter (p = 0.46), or between males and females (p = 0.35). The female night workers had significantly lower serum 25OHD levels compared to the female day workers (p = 0.01). No significant difference in serum 25OHD levels was found between the night and day male workers (p = 0.25). The number of night shifts/month was negatively correlated with 25OHD levels in both the males and females (p = 0.01 and p = 0.007, respectively). Age was positively correlated with 25OHD levels in both the males and females (p = 0.02 and p = 0.001, respectively). Body mass index was negatively associated with 25OHD levels in the whole sample (p = 0.03), but not within each gender group (p = 0.21 for the males and p = 0.09 for the females). Smoking had no significant association with 25OHD levels (p = 0.99 for the males and p = 0.22 for the females). Conclusions Our results suggest that women working night shifts are at higher risk of 25OHD deficiency, and, consequently, of other health problems linked to 25OHD deficiency. Int J Occup Med Environ Health 2016;29(5):859–870

5

Attitude of pediatricians and family physicians regarding vitamin D supplementation for the pediatric population: when, how much, and at what dose?

75%

Kara Elitok G., Bulbul L., Bulbul A., Uslu S., Zubarioglu U., Kıray Bas E., Besnili Acar D.

Family Medicine & Primary Care Review

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2018

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issue 4

332-336

6

Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland

75%

Baczyńska-Strzecha M., Kalinka J.

International Journal of Occupational Medicine and Environmental Health

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2017

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vol. 30

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issue 6

933-941

EN

Objectives Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. Results Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094). Conclusions Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933–941

7

Właściwości immunomodulacyjne witaminy D oraz jej wykorzystanie w prewencji i leczeniu wybranych jednostek chorobowych

75%

Lewandowska A.

Alcumena. Pismo Interdyscyplinarne

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2023

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issue 3(15)

99-112

EN

In the twenty-first century, we are constantly facing allergic diseases, autoimmune diseases and cancers. Despite the genetic predisposition to the above-mentioned diseases, there is a possibility of supporting the organism with substances with immunomodulatory properties, such as vitamin D. Although it has been known so far mainly for the regulation of calcium and phosphate metabolism, its role in supporting the immune system is being discovered. The evidence for this is the demonstration that genes regulated by vitamin Dencode proteins involved in the processes of cell differentiation, proliferation and apoptosis and the detection of vitamin D receptors in cells of the immune system – thymus, B and T lymphocytes and bone marrow. Vitamin D occurs in foods of animal origin in the form of cholecalciferol, and in plant products in the ergocalciferol form. Cholecalciferol can also be obtained through the synthesis by human skin under the influence of UVB radiation. In Poland, there is a common deficiency of vitamin D – during summer, on average, 50% of the population is deficient, while in the winter, this percentage increases to 80%. The deficiency may predispose to many diseases. The objective of this paper was to examine the potential impact of vitamin D in terms of preventing and/or improving selected autoimmune and allergic diseases. Clinical studies in the scientific literature have been analyzed to determine the influence of vitamin D supplementation on the prevention and/or course of cancer in adults, autoimmune diseases in adults, and allergic diseases in children and adults. The conclusions are based on a meta-analysis of 8 clinical studies and 1 in vitro study on cell culture. The results of the study show that the compensation of 25(OH)D deficiency results in a milder course of systemic lupus erythematosus and Hashimoto’s disease. The supplementation of at least 1,200 IU of vitamin D reduces the incidence of cancer by an average of 35% among adults at risk compared to people without supplementation. The recommended intake of vitamin D by pregnant women also reduces the risk of allergic diseases in children from age 1 to 10. Moreover, vitamin D (2000 IU) supplementation in adults suffering from asthma supports a milder course of asthma and reduces the incidence of upper respiratory tract infections compared to the group not using supplementation.

8

Effects of vitamin D3 supplementation on lipid profile and renal indices in rat model of drug induced renal injury

75%

Sonuga A. A., Adeyanju M. M., Ladokun O. A., Sonuga O.

European Journal of Clinical and Experimental Medicine

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2024

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issue 4

729-738

EN

Introduction and aim. Renal injury is associated with decreased renal function, hypovitaminosis D, deranged calcium-phosphate metabolism and dyslipidemia, thus increasing risk for chronic kidney disease and cardiovascular diseases. However, reports on the effects of vitamin D on drug induced renal injury are few. The aim was to investigate the possible role of vitamin D supplementation in reversing deranged lipid profile and renal function post drug induced renal injury. Material and methods. Wister male rats (36) were randomly divided into group 1, 2 and 3 (n=12). Single dose of Adriamycin was given to all except group 1(control) to induce renal injury. Group 2 left untreated, group 3 given vitamin D3 for 28 days. Serum urea, creatinine, total protein, total cholesterol (TC), triglycerides (TG), LDL-C, HDL, apolipoprotein (Apo) A and B were measured. C-reactive protein (CRP) and nitric oxide were assessed in kidney homogenate. Results. Vitamin D3 significantly brought down levels of serum creatinine, TC, LDL CRP, nitric oxide and increased the levels of Apo A, albumin, HDL. Serum urea, TG and Apo B in group 3 were not significantly different after vitamin D3 administration. Histological examination revealed improvement in glomerular messangialisation. Conclusion. Vitamin D3 may improve renal health, through its positive impact on dyslipidemia, inflammation, and oxidative stress in drug induced renal injury.

9

The role of vitamin D and its supplementation in sarcoidosis – current status

75%

Bieda A., Kondracka M., Bielecki M., Zapałowska A., Kondracki K., Szczepańska M., Kozłowski W.

European Journal of Clinical and Experimental Medicine

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2025

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issue 2

482-492

EN

Introduction and aim. Sarcoidosis is a chronic autoimmune-related inflammatory disease characterized by non-caseating granuloma formation. The macrophages accumulating in granulomas express increased 1alpha hydroxylase activity. Increased extrarenal 1,25-dihydroxyvitamin D synthesis can lead to hypercalcemia and its complications. However, 25-hydroxyvitamin D deficiency and insufficiency are virtually universal among sarcoidosis patients. The aim of this study was to explain the complex role of vitamin D and to its metabolites and discuss the possible benefits and risks associated with the administration of exogenous vitamin D to patients with sarcoidosis. Material and methods. PubMed and Scopus databases were searched for reviews about The role of vitamin D and its supplementation in sarcoidosis. The authors have analyzed a total of 107 full-text articles published between January 2000 and November 2024, with additional articles identified by bibliography analysis. Analysis of literature. The potential benefits of vitamin D supplementation in sarcoidosis are promising in terms of reducing the inflammatory response, counteracting disease progression, reducing bone fracture risk, and minimizing the pharmacotherapy needed for disease control. However, the risk of hypercalcemia should not be neglected. Conclusion. Despite the increased risk of hypercalcemia, vitamin D supplementation in patients with sarcoidosis should be considered. Each patient’s benefits-to-risks ratio of vitamin D supplementation should be assessed individually and the intervention should be closely monitored both before and during implementation.

10

Promieniowanie słoneczne a witamina D i nowotwory skóry

63%

Nowicka G.

Studia Ecologiae et Bioethicae

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2008

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vol. 6

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issue 1

6-14

EN

Solar radiation is a part of the environment of man. Ultraviolet В radiation in required for the biosynthesis of vitamin D, which is generally associated with calcium metabolism and significantly influences a wide range of metabolic systems, therefore, has a strong influence on human health. However, exposure to sunlight carries potential risks to human health. Ultraviolet radiation is a known carcinogen and excessive sunlight exposure significantly increases risk of skin cancer.

11

Procesy wpływające na zawartość witaminy D w grzybach

51%

Kobus-Cisowska J., Zawadzka A.

Zagadnienia Doradztwa Rolniczego

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2020

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issue 4 (102)

69-79

PL

Powszechnie spożywane gatunki grzybów pod wpływem działania promieni UV (światło słoneczne lub lampa UV) mogą generować istotne z punktu widzenia żywieniowego zawartości witaminy D. Główną formą witaminy D, która występuje w grzybach jest D2 (ergokalcyferol C28H44O) oraz mniejsze ilości D3 (cholekalcyferolC27H44O) i D4 (22-dihydroergokacyferol C28H46O). Witamina D3 w największych ilościach znajduje się w produktach pochodzenia zwierzęcego. Źródłem witaminy D2 są grzyby. Pomimo tego, że procesy technologiczne lub przechowywanie powodują spadek jej zawartości, zawartość D2 w grzybach może stanowić dobre jej źródło w diecie. Celem pracy była analiza aktualnych danych literaturowych w zakresie wpływu promieniowania UV na syntezę witaminy D2 w grzybach, a także wpływu ich przechowywania i obróbki termicznej na jej zawartość i biodostępność.

EN

Commonly consumed mushroom species exposed to UV radiation (sunlight or UV lamp) can generate nutritionally important amounts of vitamin D. The most common form of vitamin D in mushrooms is D2, with lesser amounts of vitamin D3 and D4, while vitamin D3 is the most common form of vitamin in animal products. Although the level of vitamin D2 in mushrooms exposed to UV radiation may decrease with storage and cooking, if they are consumed before the expiry date, the level of vitamin D2 is likely to remain above 10 μg / 100 fresh masstherefor mushrooms have the potential to be the only non-animal and unenriched food source that can provide a significant amount of vitamin D2. This review analyses current information on the role of UV radiation in enhancing concentration of vitamin D2 in mushromms, the effects of storage and cooking on D2 content, and bioavailability of vitamin D2 from mushrooms.

12

Ocena stężenia 25(OH)D u osób z zespołem metabolicznym pracujących w rolnictwie

51%

Godala M., Gaszyńska E., Moczulski D., Materek-Kuśmierkiewicz I., Krzyżak M.

Medycyna Pracy

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2021

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vol. 72

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issue 1

9-18

EN

Background: Polish data on vitamin D deficiency in the population are incomplete. Vitamin D deficiency seems to be common, but there is a lack of studies concerning the concentration of 25(OH)D in people with high UV exposure. The aim of this study was to evaluate the plasma concentration of 25(OH)D in people with and without metabolic syndrome (MS), working in agriculture, the prevalence of its deficiency in these workers, and the correlation between the plasma concentration of 25(OH)D and traditional biomarkers of cardiovascular diseases. Material and Methods: The study included 332 people working in agriculture in the Łódź voivodeship, including 231 people with MS and 101 healthy ones. The plasma concentration of 25(OH)D was assessed using the chemiluminescent immunoassay technology. The vitamin D intake was assessed using a 24-h recall questionnaire using Diet 5.0 software. Results: The mean plasma concentration of 25(OH)D was 13.64±8.01 ng/ml in MS workers, and it was significantly lower than in the healthy ones (26.61±10.12 ng/ml, p < 0.00001); the highest concentration of 25(OH)D was noted in summer months. Deficient plasma concentrations of 25(OH)D were found significantly more often in MS workers than in the controls (81.82% and 20.79%, respectively, p < 0.00001). No correlation was found between the plasma vitamin D concentration and its dietary intake. The plasma concentration of 25(OH)D correlated with age of the examined workers (r = –0.28, p = 0.023), high density lipoprotein concentration (r = 0.19, p = 0.036) and glucose concentration (Rho = –0.24, p = 0.02). A multivariate analysis of variance demonstrated that the body mass index affected significantly the mean value of the 25(OH)D concentration in MS workers. Conclusions: The concentration of vitamin D in the plasma of workers with MS was significantly lower than in the healthy controls despite the same high UV exposure; these workers also manifested significantly higher 25(OH)D deficiency than the control subjects. This study indicates the need for further research on the concentration of 25(OH)D in people with metabolic disorders regardless of UV exposure and vitamin D intake with a diet.

PL

Wstęp: Dane dotyczące stanu odżywienia witaminą D populacji polskiej są niepełne. Niedobory witaminy D wydają się powszechne, jednak nie odnaleziono polskich badań, które weryfikowałyby stężenie 25-hydroksywitaminy D [25(OH)D] u osób intensywnie eksponowanych na promieniowanie ultrafioletowe (UV). Celem pracy była ocena stężenia 25(OH)D w osoczu osób z zespołem metabolicznym (ZM) pracujących w rolnictwie, częstość jej niedoborów u tych osób oraz zależność między stężeniem 25(OH)D w osoczu a tradycyjnymi biomarkerami chorób sercowo-naczyniowych. Materiał i metody: W badaniu wzięło udział 332 mieszkańców województwa łódzkiego pracujących w rolnictwie, w tym 231 osób z ZM i 101 zdrowych. Stężenie 25(OH)D w osoczu oceniano z użyciem testu wykorzystującego technologię chemiluminescencyjnych testów immunologicznych. Spożycie witaminy D z dietą oceniano za pomocą programu Dieta 5.0 na podstawie 24-godzinnych wywiadów żywieniowych. Wyniki: Średnie stężenie 25(OH)D w osoczu pracowników z ZM wynosiło 13,64±8,01 ng/ml i było istotnie niższe niż w grupie badanych bez ZM (26,61±10,12 ng/ml, p < 0,00001). Najwyższe średnie stężenie 25(OH)D odnotowano w miesiącach letnich. U pracowników z ZM istotnie częściej niż w grupie bez ZM stwierdzono deficytowe stężenie 25(OH)D w osoczu (odpowiednio, 81,82% i 20,79%, p < 0,00001). Stwierdzono brak korelacji między stężeniem 25(OH)D a jej spożyciem z dietą. Stężenie 25(OH)D korelowało z wiekiem (r = –0,28, p = 0,023) oraz stężeniami cholesterolu HDL (r = 0,19, p = 0,036) i glukozy (Rho = –0,24, p = 0,02) w badanej grupie rolników. Wieloczynnikowa analiza wariancji wykazała, że u pracowników z ZM czynnikiem wpływającym istotnie na średnią wartość stężenia 25(OH)D był wskaźnik masy ciała. Wnioski: Stężenie witaminy D w osoczu osób z ZM było istotnie mniejsze niż u osób zdrowych mimo jednakowej, wysokiej ekspozycji na promieniowanie UV. Ponadto u osób z ZM istotnie częściej stwierdzano deficytowe stężenie 25(OH)D niż u badanych bez ZM. Uzyskane wyniki wskazują na konieczność prowadzenia dalszych badań dotyczących stężenia 25(OH)D u osób z chorobami metabolicznymi, niezależnie od wielkości ekspozycji na promieniowanie UV i spożycia witaminy D z dietą.

13

Problem podwyższonego stężenia witaminy D3 w grupie pacjentów hospitalizowanych w klinice geriatrii

51%

Żórawska J., Szczepaniak W.

Medycyna Pracy

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2024

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vol. 75

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issue 3

286-292

EN

Background Taking into account the multi-directional beneficial effects of vitamin D3 and its widespread deficiency, regular supplementation is recommended. However, more and more attention is being paid to the risk of overdose with supplemented vitamin D3 and the associated serious health consequences. Material and Methods The concentration of 25-hydroxyvitamin D (25(OH)D) is a routine test recommended upon admission to the Geriatrics Clinic of Wroclaw Medical University. The aim of the study was to analyze the results from January 2018 to June 2023. Additionally, information on the reported symptoms, gender and age of people with an increased level of vitamin D3 was collected. Results Analyzing a group of 1400 patients, it was noted that within 5 years, vitamin D3 concentrations exceeding the recommended level were recorded in 7 patients, including 3 with toxic levels. All abnormal results occurred in women. The most frequently reported symptoms included general weakness, lower limbs and joint pain, sleep disorders, low mood. People with toxic concentrations reported dizziness. In seniors there is a gradual increase in vitamin D concentration and its deficiency is less common. Higher concentrations were recorded in the group of older seniors, and concentrations considered toxic occur in the population >74 years of age. Supplements and drugs with vitamin D are most often used without consulting a doctor, without determining the appropriate dose, or without assessing the concentration of 25(OH)D in the serum. Conclusions To prevent vitamin D deficiency in seniors, doses >4000 IU daily are not recommended. It is advisable to check all medications and supplements taken at each doctor’s visit in terms of duplicating treatment with vitamin D. It is advisable to assess the status of vitamin D supply the concentration of 25(OH)D in order to select the appropriate dose. Assessment of 1,25-dihydroxyvitamin D concentration is recommended in cases of vitamin D toxicity.

PL

Wstęp Biorąc pod uwagę wielokierunkowe korzystne działanie witaminy D3 i jej rozpowszechniony niedobór także w populacji polskiej, powszechnie zaleca się jej regularną suplementację. Coraz więcej uwagi zwraca się jednak na ryzyko przedawkowania suplementowanej witaminy D3 i związane z tym poważne skutki zdrowotne. Materiał i metody Kontrola stężenia 25-hydroksywitaminy D (25(OH)D) jest rutynowym badaniem zalecanym przy przyjęciu do Kliniki Geriatrii Uniwersytetu Medycznego we Wrocławiu. Celem pracy była analiza uzyskanych wyników w okresie od stycznia 2018 r. do czerwca 2023 r. Dodatkowo zebrano informacje odnośnie do zgłaszanych objawów, płci i wieku osób ze stwierdzonym podwyższonym stężeniem witaminy D3. Wyniki Analizując grupę 1400 pacjentów, odnotowano, że w ciągu 5 lat wartości przekraczające zalecane stężenia witaminy D3 odnotowano u 7 pacjentów, w tym u 3 był to poziom toksyczny. Wszystkie nieprawidłowe wyniki dotyczyły kobiet. W analizowanej populacji wśród najczęściej zgłaszanych objawów dominowały skargi na ogólne osłabienie, bóle kończyn dolnych, bóle stawów, zaburzenia snu i obniżenie nastroju. Dodatkowo osoby ze stężeniem toksycznym zgłaszały zawroty głowy. Analiza wykazała, że w populacji geriatrycznej obserwuje się stopniowy wzrost stężenia witaminy D i rzadziej występuje jej niedobór. Wyższe i toksyczne stężenia odnotowano u pacjentów >74 r.ż. Suplementy i leki z witaminą D są najczęściej stosowane bez konsultacji z lekarzem, bez ustalenia właściwej dawki i bez oceny stężenia 25(OH)D w surowicy. Wnioski W prewencji niedoboru witaminy D u osób >65 r.ż. nie należy stosować dawek >4000 j.m./d. Wskazana jest ocena wszystkich przyjmowanych przez seniorów leków i suplementów diety przy każdej wizycie lekarskiej pod względem powielania leczenia także witaminą D. W populacji osób starszych wskazana jest ocena stanu zaopatrzenia w witaminę D poprzez oznaczenia stężenia 25(OH)D w celu doboru właściwej dawki i korekty suplementowania. Oznaczenie stężenia 1,25-dihydroksywitaminy D jest wskazane w przypadku zatrucia witaminą D w celu wykluczenia jej pozanerkowej hydroksylacji.

Refine search results

Serum levels of vitamin D and tumour necrosis factor-alpha in adults with metabolic syndrome

Thyroid functioning, adipocytokines, bone turnover and vitamin D - review of literature

Nutritional status of frail elderly

Determinants of vitamin D status among Jordanian employees: Focus on the night shift effect

Attitude of pediatricians and family physicians regarding vitamin D supplementation for the pediatric population: when, how much, and at what dose?

Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland

Właściwości immunomodulacyjne witaminy D oraz jej wykorzystanie w prewencji i leczeniu wybranych jednostek chorobowych

Effects of vitamin D3 supplementation on lipid profile and renal indices in rat model of drug induced renal injury

The role of vitamin D and its supplementation in sarcoidosis – current status

Promieniowanie słoneczne a witamina D i nowotwory skóry

Procesy wpływające na zawartość witaminy D w grzybach

Ocena stężenia 25(OH)D u osób z zespołem metabolicznym pracujących w rolnictwie

Problem podwyższonego stężenia witaminy D3 w grupie pacjentów hospitalizowanych w klinice geriatrii